942142-51-0
942142-51-0 structure
- Name: VTP-27999
- Chemical Name: methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate
- CAS Number: 942142-51-0
- Molecular Formula: C26H41ClN4O5
- Molecular Weight: 525.08100
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Renin
- Create Date: 2018-12-04 08:14:17
- Modify Date: 2024-01-03 18:03:02
-
VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.Ic50 value:Target: Renin
| Name | methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate |
|---|---|
| Synonyms |
Methyl (2-{(R)-(3-Chlorophenyl)[(3r)-1-({(2s)-2-(Methylamino)-3-[(3r)-Tetrahydro-2h-Pyran-3-Yl]propyl}carbamoyl)piperidin-3-Yl]methoxy}ethyl)carbamate
Methyl (2-((R)-(3-chlorophenyl)((R)-1-(((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propyl)carbamoyl)piperidin-3-yl)methoxy)ethyl)carbamate QC-4593 VTP-27999 |
| Description | VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.Ic50 value:Target: Renin |
|---|---|
| Related Catalog | |
| References |
| Density | 1.178g/cm3 |
|---|---|
| Boiling Point | 703.1ºC at 760 mmHg |
| Molecular Formula | C26H41ClN4O5 |
| Molecular Weight | 525.08100 |
| Flash Point | 379ºC |
| Exact Mass | 524.27700 |
| PSA | 101.16000 |
| LogP | 4.69060 |
| Index of Refraction | 1.537 |
| Storage condition | 2-8℃ |
|
~91%
942142-51-0 |
| Literature: VITAE PHARMACEUTICALS, INC.; CLAREMON, David, A.; SIMPSON, Robert, D.; JIA, Lanqi Patent: WO2011/17533 A1, 2011 ; Location in patent: Page/Page column 24 ; |
| Precursor 1 | |
|---|---|
| DownStream 0 | |