71835-85-3

71835-85-3 structure

Name: Phenethyl ferulate
Chemical Name: 2-phenylethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
CAS Number: 71835-85-3
Molecular Formula: C₁₈H₁₈O₄
Molecular Weight: 298.33
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2017-01-18 03:25:49
Modify Date: 2025-08-14 12:00:35
Phenethyl ferulate is a major constituent ofQianghuo, shows inhibitory activity against cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) with IC50 values of 4.35 μM and 5.75 μM, respectively[1].

Name	2-phenylethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
Synonyms	Phenyethyl 3-methylcaffeate 2-Phenylethyl 3-(4-hydroxy-3-methoxyphenyl)-2-propenoate 2-phenylethyl (2E)-3-[4-hydroxy-3-(methyloxy)phenyl]prop-2-enoate Phenylethyl 3-methylcaffeate Caffeic Acid 3-Methyl Phenethyl Ester 2-Propenoic acid,3-(4-hydroxy-3-methoxyphenyl)-,2-phenylethyl ester

Description	Phenethyl ferulate is a major constituent ofQianghuo, shows inhibitory activity against cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) with IC50 values of 4.35 μM and 5.75 μM, respectively[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase
Target	COX:4.35 μM (IC50) 5-LOX:5.75 μM (IC50)
References	[1]. S Zschocke, et al. 5-Lipoxygenase and cyclooxygenase inhibitory active constituents from Qianghuo (Notopterygium incisum). Planta Med. 1997 Jun;63(3):203-6.