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72088-94-9

72088-94-9 structure
72088-94-9 structure
  • Name: 5(6)-Carboxyfluorescein
  • Chemical Name: 5(6)-Carboxyfluorescein
  • CAS Number: 72088-94-9
  • Molecular Formula: C21H12O7
  • Molecular Weight: 376.32
  • Catalog: Dye Reagents
  • Create Date: 2018-08-13 07:42:30
  • Modify Date: 2024-01-03 18:29:57
  • 5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume.
Name 5(6)-Carboxyfluorescein
Synonyms Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 3',6'-dihydroxy-3-oxo-, compd. with 3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid (1:1)
3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid - 3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid (1:1)
MFCD00151081
Fluoresceincarboxylic Acid
EINECS 276-331-1
Description 5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume.
Related Catalog
References

[1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9.

[2]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66.
Melting Point 275 °C
Molecular Formula C21H12O7
Molecular Weight 376.32
PSA 226.58000
LogP 6.72800
Storage condition Store at 2-8
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36
Safety Phrases 37/39-26-36
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS CQ7700000
HS Code 29335995
HS Code 29335995
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