5(6)-Carboxyfluorescein

Modify Date: 2024-01-03 18:29:57

5(6)-Carboxyfluorescein structure	Common Name	5(6)-Carboxyfluorescein
	CAS Number	72088-94-9	Molecular Weight	376.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₂O₇	Melting Point	275 °C
	MSDS	Chinese USA	Flash Point	N/A

Use of 5(6)-Carboxyfluorescein

5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume.

Name	5(6)-Carboxyfluorescein
Synonym	More Synonyms

Description	5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
References	[1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9. [2]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

References

[1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9.

[2]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66.

Melting Point	275 °C
Molecular Formula	C₂₁H₁₂O₇
Molecular Weight	376.32
PSA	226.58000
LogP	6.72800
Storage condition	Store at 2-8

5(6)-Carboxyfluorescein MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36
Safety Phrases	37/39-26-36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	CQ7700000
HS Code	29335995

HS Code	29335995

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MFCD00151081

Fluoresceincarboxylic Acid

EINECS 276-331-1