Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Swertianolin
Price: ￥2748.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: SWERTIANOLIN
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

23445-00-3

23445-00-3 structure

23445-00-3 structure

Name: Swertianolin
Chemical Name: swertianolin
CAS Number: 23445-00-3
Molecular Formula: C₂₀H₂₀O₁₁
Molecular Weight: 436.366
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-02-26 08:00:00
Modify Date: 2024-01-02 09:26:35
Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity[1][2].

Name	swertianolin
Synonyms	5,8-Dihydroxy-3-methoxy-9-oxo-9H-xanthen-1-yl β-D-glucopyranoside Sw-bromoacetophenone semicarbazone 2-bromo-1-phenyl-ethanone semicarbazone bellidifolin 8-O-glucopyranoside 9H-Xanthen-9-one, 1-(β-D-glucopyranosyloxy)-5,8-dihydroxy-3-methoxy- 2-Brom-1-phenyl-aethanon-semicarbazon SWERTIANOLIN phenacyl bromide semicarbazone

Description	Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Research Areas >> Inflammation/Immunology Signaling Pathways >> Neuronal Signaling >> AChE Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Urbain A, et al. Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors. Planta Med. 2004 Oct;70(10):1011-4. [2]. Xiu-Qiao Zhang, et al. Anti-HBV Activities of Xanthones From Swertia Punicea Hemsl. N A J Med Sci. 2014;7(2):72-74.

Density	1.7±0.1 g/cm3
Boiling Point	806.3±65.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₀O₁₁
Molecular Weight	436.366
Flash Point	287.7±27.8 °C
Exact Mass	436.100555
PSA	179.28000
LogP	-1.13
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.705
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZD6057000

CHEMICAL NAME :: Xanthen-9-one, 5,8-dihydroxy-1-(beta-D-glucopyranosyloxy)-3-methoxy-

CAS REGISTRY NUMBER :: 23445-00-3

LAST UPDATED :: 199503

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H20-O11

MOLECULAR WEIGHT :: 436.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 150,141,1985

Precursor 0
DownStream 4
2798-25-6 2280-44-6 1139-97-5 5557-27-7