Swertianolin

Modify Date: 2024-01-02 09:26:35

Swertianolin structure	Common Name	Swertianolin
	CAS Number	23445-00-3	Molecular Weight	436.366
	Density	1.7±0.1 g/cm3	Boiling Point	806.3±65.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₀O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	287.7±27.8 °C

Use of Swertianolin

Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity[1][2].

Name	swertianolin
Synonym	More Synonyms

Description	Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Research Areas >> Inflammation/Immunology Signaling Pathways >> Neuronal Signaling >> AChE Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Urbain A, et al. Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors. Planta Med. 2004 Oct;70(10):1011-4. [2]. Xiu-Qiao Zhang, et al. Anti-HBV Activities of Xanthones From Swertia Punicea Hemsl. N A J Med Sci. 2014;7(2):72-74.

Description

Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity[1][2].

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> HBV

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Neuronal Signaling >> AChE

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Urbain A, et al. Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors. Planta Med. 2004 Oct;70(10):1011-4.

[2]. Xiu-Qiao Zhang, et al. Anti-HBV Activities of Xanthones From Swertia Punicea Hemsl. N A J Med Sci. 2014;7(2):72-74.

Density	1.7±0.1 g/cm3
Boiling Point	806.3±65.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₀O₁₁
Molecular Weight	436.366
Flash Point	287.7±27.8 °C
Exact Mass	436.100555
PSA	179.28000
LogP	-1.13
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.705
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZD6057000

CHEMICAL NAME :: Xanthen-9-one, 5,8-dihydroxy-1-(beta-D-glucopyranosyloxy)-3-methoxy-

CAS REGISTRY NUMBER :: 23445-00-3

LAST UPDATED :: 199503

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H20-O11

MOLECULAR WEIGHT :: 436.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 150,141,1985