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Dayang Chem (Hangzhou) Co., Ltd.
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Henan Tianfu Chemical Co., Ltd.
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Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: L(-)-Glutathione
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27025-41-8

27025-41-8 structure

27025-41-8 structure

Name: L(-)-Glutathione
Chemical Name: glutathione disulfide
CAS Number: 27025-41-8
Molecular Formula: C₂₀H₃₂N₆O₁₂S₂
Molecular Weight: 612.631
Catalog: Biochemical Peptide
Create Date: 2018-04-26 08:00:00
Modify Date: 2026-06-30 13:23:41
Glutathione oxidized is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent.

Name	glutathione disulfide
Synonyms	Glutathione disulfide Glutathione (oxidized form) L-Glutathione (oxidized) L-Glutathione (oxidized) CYCLIC(GAMMA-GLU-CYS-GLY)2 Glutathione, oxidized,L-Glutathione oxidized, GSSG, Glutathiol GLT1JP-IN (L-GLUTATHIONE RED (2S,5Z,2'S,5'E)-5,5'-[Disulfanediylbis({(2R,3Z)-3-[(carboxymethyl)imino]-3-hydroxy-1,2-propanediyl}nitrilo)]bis(2-amino-5-hydroxypentanoic acid) (non-preferred name) oxigluthione glutathonedisulfide glutathione-ssg Oxiglutatione (-)-GLUTATHIONE, OXIDIZED Glutathione IMpurity C (Disulfide IMpurity) GSSC MFCD00063106 L(-)-Glutathione, oxidized, hydrate N,N'-(Dithiobis(1-((carboxymethyl)carbamoyl)ethylene))di-L-glutamine N-(N-g-Glutamyl-cysteinyl)glycine-(2,2)-disulfide Glutathiol GAMMA-L-GLUTAMYL-L-CYSTEINYLGLYCINE OXIDIZED N,N’-[dithiobis[1-[(cboxymethyl)cbamoyl]ethylene]]di-,L-Glutamine S,S’-Ethylenebis(glutathione) (2S,2'S)-5,5'-[Disulfanediylbis({(2R)-3-[(carboxymethyl)amino]-3-oxo-1,2-propanediyl}imino)]bis(2-amino-5-oxopentanoic acid) L-GLUTATHIONE OXIDISED Glycine,L-.gamma.-glutamyl-L-cysteinyl-,2,2’-disulfide [GAMMA-GLU-CYS-GLY] [GAMMA-GLU-CYS-GLY] glutathione oxidized form Oxidized glutathione APPROVAL REQ GLUTATHIONE OXIDIZED CYCLIC(GAMMA-GLU-CYS-GLY) L(-)-Glutathionehydrate GLUTATHIONE OXIDIZED FORM FREE ACIDAD E II L(-)-Glutathione, oxidized N-(N-.gamma.-Glutamyl-cysteinyl)glycine-2,2-disulfide GLUTATHIONE, OXIDIZED FORM oxidizedglutathione White lyophilizate GSSG,Glutathiol N,N'-Bis(cboxymethyl)-Nα,Nα'-bis(γ-glutamyl)-L-cystinamide Glutathiol,GSSG 3,3'-Dithiobis[N-(cboxymethyl)-N2-(γ-glutamyl)alaninamide] l-gamma-glutamyl-l-cysteinyl glycine L-Glutathione oxidized,GSSG, Glutathiol N,N'-[Dithiobis[1-[(cboxyMethyl)cbaMoyl]ethylene]]diglutaMine GLUTATHIONE OXIDISED extrapure L-Glutathione oxidized n’-(dithiobis(1-((cboxymethyl)cbamoyl)ethylene))di-l-glutamin GLUTATHIONE DISULFIDE L-.GLUTATHIONE (OXIDIZED) [N-(N-L-G-GLUTAMYL-L-CYSTEINYL)GLYCINE] glutathionedisulphide GSH disulfide L-Glutathione oxidized, Glutathiol, GSSG NOV-002 GSSG Glutathione(Oxidized Form), free acid L-GLUTATHIONE OXIDIZED glycine,l-gamma-glutamyl-l-cysteinyl-,(2,2’)-disulfide Oxyglutatione l-oxidizedglutathione glutathione oxidized Glutathione Oxydized L-Glutathione oxidized Vetec(TM) ade, >= EINECS 248-170-7 GLUTATHIONE OXIDIZED FORM FREE ACIDLYOP HILIZED POW n-(n-gamma-glutamyl-cysteinyl)glycine-(2,2)-disulfide bi(glutathion-S-yl) GSSG oxidized form glutathione, oxidised (GAMMA-GLU-CYS-GLY)2 L-GLUTATHIONE (OXIDIZED FORM) (2S,2'S)-5,5'-[Disulfanediylbis({(2R)-3-[(carboxymethyl)amino]-3-oxopropane-1,2-diyl}imino)]bis(2-amino-5-oxopentanoic acid) (non-preferred name) Glutathiol, GSSG

Description	Glutathione oxidized is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent.
Related Catalog	Research Areas >> Metabolic Disease Natural Products >> Others
Target	Human Endogenous Metabolite
References	[1]. Nur E, et al. Increased efflux of oxidized glutathione (GSSG) causes glutathione depletion and potentially diminishes antioxidant defense in sickle erythrocytes. Biochim Biophys Acta. 2011 Nov;1812(11):1412-7.

Density	1.7±0.1 g/cm3
Boiling Point	976.3±75.0 °C at 760 mmHg
Melting Point	178 °C (dec.)(lit.)
Molecular Formula	C₂₀H₃₂N₆O₁₂S₂
Molecular Weight	612.631
Flash Point	544.3±37.1 °C
Exact Mass	612.151978
PSA	368.24000
LogP	1.91
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.677
Storage condition	2~8°C
Water Solubility	soluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MC0556500

CHEMICAL NAME :: Glycine, L-gamma-glutamyl-L-cysteinyl-, (2,2')-disulfide

CAS REGISTRY NUMBER :: 27025-41-8

LAST UPDATED :: 199212

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C20-H32-N6-O12-S2

MOLECULAR WEIGHT :: 612.70

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,6793,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,6793,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,6793,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,6793,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,6793,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 23,6793,1989

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	MC0556500

Precursor 9
70-18-8 86810-11-9 105664-16-2 28104-73-6
76726-99-3 86810-08-4 86810-07-3 86810-09-5
86810-10-8
DownStream 8
70-18-8 13081-14-6 6477-52-7 75027-08-6
1892-29-1 636-58-8 4344-84-7 7729-20-6

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