Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: COUMACHLOR
Price: ￥1138.0/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Coumachlor
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

81-82-3

81-82-3 structure

81-82-3 structure

Name: COUMACHLOR
Chemical Name: coumachlor
CAS Number: 81-82-3
Molecular Formula: C₁₉H₁₅ClO₄
Molecular Weight: 342.773
Catalog: analytical chemistry Standard Agricultural and environmental standards
Create Date: 2018-07-11 12:04:36
Modify Date: 2024-01-02 07:14:32
Coumachlor is a first genereation anticoagulant rodenticide which blocks formation of prothrombin and inhibits blood coagulation causing death by internal haemorrhage.

Name	coumachlor
Synonyms	UNII:UCD8XZW42P 3-(1-(4-Chlorophenyl)-3-oxobutyl)-4-hydroxy-2H-1-benzopyran-2-one (9CI) MFCD00012094 2H-1-Benzopyran-2-one, 3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy- 3-(a-Acetonyl-p-chlorobenzyl)-4-hydroxycoumarin tomorin 3-[(1RS)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxycoumarin 3-(a-p-Chlorophenyl-b-acetylethyl)-4-hydroxycoumarin 3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one Coumachlor Geigy Rodenticide Exp.332 FAMARIN rac-3-[(1R)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one 3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-chromen-2-one ratilan P-CHLOROWARFARIN cumachloor kumachlor (±)-3-(1-(p-Chlorophenyl)-3-oxobutyl)-4-hydroxycoumarin EINECS 201-378-1 (±)-Coumachlor

Density	1.4±0.1 g/cm3
Boiling Point	543.1±50.0 °C at 760 mmHg
Melting Point	168-170 °C(lit.)
Molecular Formula	C₁₉H₁₅ClO₄
Molecular Weight	342.773
Flash Point	282.3±30.1 °C
Exact Mass	342.065887
PSA	67.51000
LogP	4.01
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.641

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN4830000

CHEMICAL NAME :: Coumarin, 3-(alpha-acetonyl-p-chlorobenzyl)-4-hydroxy-

CAS REGISTRY NUMBER :: 81-82-3

BEILSTEIN REFERENCE NO. :: 1689759

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H15-Cl-O4

MOLECULAR WEIGHT :: 342.79

WISWESSER LINE NOTATION :: T66 BOVJ DY1V1&R DG& EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 187 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 33 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 392 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 221 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H373-H412
Precautionary Statements	P273
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R48/22;R52/53
Safety Phrases	S37-S61
RIDADR	UN 2811 6.1/PG 1
WGK Germany	2
RTECS	GN4830000
Packaging Group	II
Hazard Class	6.1(a)

3160-40-5 structure

3160-40-5

1076-38-6 structure

1076-38-6

~0%

81-82-3 structure

81-82-3

81-82-3 structure

81-82-3

Literature: Advanced Synthesis and Catalysis, , vol. 355, # 13 p. 2538 - 2543

3160-40-5 structure

3160-40-5

1076-38-6 structure

1076-38-6

~76%

81-82-3 structure

81-82-3

Literature: Tetrahedron, , vol. 66, # 51 p. 9708 - 9713

81-82-3 structure

81-82-3

~%

81-82-3 structure

81-82-3

81-82-3 structure

81-82-3

Literature: Analytical Chemistry, , vol. 73, # 22 p. 5499 - 5508

1076-38-6 structure

1076-38-6

30626-03-0 structure

30626-03-0

~%

81-82-3 structure

81-82-3

81-82-3 structure

81-82-3

Literature: Angewandte Chemie - International Edition, , vol. 42, # 40 p. 4955 - 4957

1076-38-6 structure

1076-38-6

104-88-1 structure

104-88-1

55831-54-4 structure

55831-54-4

~%

81-82-3 structure

81-82-3

Detail

Literature: Tetrahedron Asymmetry, , vol. 12, # 5 p. 707 - 709

Precursor 5
3160-40-5 1076-38-6 81-82-3 104-88-1
55831-54-4
DownStream 1
81-82-3