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31430-15-6

31430-15-6 structure

31430-15-6 structure

Name: Flubendazole
Chemical Name: flubendazole
CAS Number: 31430-15-6
Molecular Formula: C₁₆H₁₂FN₃O₃
Molecular Weight: 313.283
Catalog: API Antiparasitic drug Anti-amebiasis and anti-trichomoniasis drugs
Create Date: 2018-08-27 10:35:54
Modify Date: 2024-01-02 18:53:59
Flubendazole is a potent broad spectrum anthelmintic.Target: AntiparasiticFlubendazole is an anthelmintic. It is also available for human use to treat worm infections[1].

Name	flubendazole
Synonyms	Biovermin Methyl (5-(4-fluorobenzoyl)-1H-benzo[d]imidazol-2-yl)carbamate Flubendazole [5-(4-Fluorobenzoyl)benzimidazol-2-yl]carbamic Acid Methyl Ester Flutelmium EINECS 250-624-4 FLUVERNAL Flubendazol,Flumoxanal,Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate [5-(4-Fluorobenzoyl)-1H-benzimidazol-2-yl]carbamic Acid Methyl Ester Flubenol fluvermal Flumoxal Carbamic acid, N-[5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]-, methyl ester Flumoxanal (Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate methyl {6-[(4-fluorophenyl)carbonyl]-1H-benzimidazol-2-yl}carbamate Flubenvet Carbamicacid, [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]-methylester Methyl {5-[(4-fluorophenyl)carbonyl]-1H-benzimidazol-2-yl}carbamate MFCD00871999 FLUMOXANAL Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate Methyl [5-(4-Fluorobenzoyl)benzimidazol-2-yl]carbamate 5-(p-Fluorobenzoyl)-2-benzimidazolecarbamic Acid Methyl Ester FLUMOXANE Methyl-{5-[(4-fluorphenyl)carbonyl]-1H-benzimidazol-2-yl}carbamat carbamic acid, [6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]-, methyl ester

Description	Flubendazole is a potent broad spectrum anthelmintic.Target: AntiparasiticFlubendazole is an anthelmintic. It is also available for human use to treat worm infections[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection
References	[1]. http://www.patentstorm.us/patents/5824336/description.html

Density	1.4±0.1 g/cm3
Melting Point	290°C
Molecular Formula	C₁₆H₁₂FN₃O₃
Molecular Weight	313.283
Exact Mass	313.086273
PSA	84.08000
LogP	3.05
Index of Refraction	1.685
Storage condition	-20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD6497500

CHEMICAL NAME :: 2-Benzimidazolecarbamic acid, 5-(p-fluorobenzoyl)-, methyl ester

CAS REGISTRY NUMBER :: 31430-15-6

LAST UPDATED :: 199410

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C16-H12-F-N3-O3

MOLECULAR WEIGHT :: 313.31

WISWESSER LINE NOTATION :: T56 BM DNJ CMVO1 GVR DF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >2560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 320 mg/kg

SEX/DURATION :: female 8-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1280 mg/kg

SEX/DURATION :: female 8-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - gastrointestinal system

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

REFERENCE :: PCBRD2 Progress in Clinical and Biological Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1975- Volume(issue)/page/year: 340E,225,1990

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
RTECS	DD6497500
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%