3476-86-6
3476-86-6 structure
- Name: SU5205
- Chemical Name: (E)-3-[(4-fluorophenyl)methylidene]-1,3-dihydro-2H-indol-2-one
- CAS Number: 3476-86-6
- Molecular Formula: C15H10FNO
- Molecular Weight: 239.24400
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
- Create Date: 2016-12-04 02:21:25
- Modify Date: 2024-01-11 00:28:12
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SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM[1].
| Name | (E)-3-[(4-fluorophenyl)methylidene]-1,3-dihydro-2H-indol-2-one |
|---|---|
| Synonyms |
3-[(E)-(4-fluorophenyl)methylidene]-1,3-dihydro-2H-indol-2-one
(E)-3-(4-fluorobenzylidene)indolin-2-one SU 5205 |
| Description | SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
Flk-1:9.6 μM (IC50) |
| In Vitro | SU5205 inhibits ligand-induced endothelial mitogenesis for VEGF with an IC50 of 5.1 μM[1]. |
| References |
| Molecular Formula | C15H10FNO |
|---|---|
| Molecular Weight | 239.24400 |
| Exact Mass | 239.07500 |
| PSA | 29.10000 |
| LogP | 3.45640 |
| Storage condition | -20℃ |