2447-57-6
2447-57-6 structure
- Name: Sulfadoxine
- Chemical Name: sulfadoxine
- CAS Number: 2447-57-6
- Molecular Formula: C12H14N4O4S
- Molecular Weight: 310.329
- Catalog: API Antibiotics Other antibiotics
- Create Date: 2018-02-15 08:00:00
- Modify Date: 2026-07-01 19:52:19
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Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract and malarial infections.Target: AntiparasiticSulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide. Sulfadoxine is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates; they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability [1, 2].
| Name | sulfadoxine |
|---|---|
| Synonyms |
Sulfadoxine BP2000/25
C16990600 Sulfadoxine SulfadoxineBp98/23 Sulphadoxine 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide,Sulfadoxin Sulfadoxine, 10 mM in DMSO SulphodoxiMe sulphormethoxine 4-azanyl-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide 6-(4-aminobenzenesulfonamide)-4,5-dimethoxypyrimidine 4-Amino-N-(5,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide fanasil Sulfadumoxine Zhou Xiao sulfonamide Sulfadoxine in methanol Sulfadoxin > sulformethoxine Sulfadimoxine SULFADOXIN VETRANAL (4-AMINO-N-(5,6-DIME ro4-4393 4-amino-N-[5,6-bis(methyloxy)pyrimidin-4-yl]benzenesulfonamide 4-AMINO-N-(5,6-DIMETHOXY-4-PYRIMIDINYL)BENZENESULFONAMIDE 4-amino-N-(4',5'-dimethoxy-6'-pyrimidinyl) benzene sulphonamide Fansid(suldfadoxine and pyrimethamine) 4-amino-N-(5,6-diméthoxypyrimidin-4-yl)benzènesulfonamide fanzil 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide N1-(5,6-DiMethoxy- 4-pyriMidinyl)sulfanilaMide Sulphadoxine BP98 6-(4,5-dimethoxy)pyrimidinesulfanilamide sulphadoxin Sulfadoxine 100 μg/ml Methanol 6-(4-aminobenzenesulfonamido)-4,5-dimethoxypyrimidine N'-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide Sulfadoxine Solution in Methanol, 100μg/mL 4-Amino-N-(5,6-Dimethoxypyrimidin-4-Yl)Benzenesulfonamide Sulfamethoxine N1-(5,6-dimethoxypyrimidin-4-yl)sulphanilamide n’-(5,6-dimethoxy-4-pyrimidyl)sulfanilamide Sulfadoxine //BP wr4873 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulphonamide sulforthomidine 4-AMINO-N-(5,6-DIMETHOXY-4-PYRIMIDINYL)- BENZENESULFONAMID Sulfadoxine Standd 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide Sulfadoxine CRS 4-Amino-N-(5,6-dimethoxypyrimidin-4-yl)benzolsulfonamid 4-amino-N-(2-hydroxy-6-methoxypyrimidin-4-yl)benzene-1-sulfonamide 4-amino-n-(5,6-dimethoxy-4-pyrimidinyl)-benzenesulfonamid 4-sulfanilamido-5,6-dimethoxypyrimidine SULFADOXINE(SDM '') sulphadoxine-pyrimethamine SULPHADOXINE BP SULFADOXIN Factory Supply High Quality Sulphadoxine Sulfadoxin 1000 μg/mL in Acetonitrile Sulformetoxine SULFADOXINE Benzenesulfonamide, 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl) Sulfadoxine F3C3360.999mg/mg(ai) N-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide Sulfadoxine Solution, 100ppm SULFADOXINE(20FINE POWDER)/ SULFADOXINE Sulphadoxine +Pyrimethamine 500 mg/25 mg Tablet sulphadoxine |
| Description | Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract and malarial infections.Target: AntiparasiticSulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide. Sulfadoxine is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates; they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability [1, 2]. |
|---|---|
| Related Catalog | |
| References |
[1]. http://www.malaria-ipca.com/sulphadoxine_pyrimethamine.html |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 522.8±60.0 °C at 760 mmHg |
| Melting Point | 190-194ºC |
| Molecular Formula | C12H14N4O4S |
| Molecular Weight | 310.329 |
| Flash Point | 270.0±32.9 °C |
| Exact Mass | 310.073578 |
| PSA | 124.81000 |
| LogP | 0.34 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.623 |
| Water Solubility | Soluble in ethanol & ammonium hydroxide (9:1) at 20mg/ml |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| RTECS | DA9500000 |
| HS Code | 2935009090 |
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |