71142-71-7

71142-71-7 structure

Name: H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt
Chemical Name: H-D-Phe-Pro-Arg-chloromethylketone
CAS Number: 71142-71-7
Molecular Formula: C₂₁H₃₁ClN₆O₃
Molecular Weight: 450.96
Catalog: Biochemical Amino acids and their derivatives Arginine derivatives
Create Date: 2018-11-25 00:28:51
Modify Date: 2026-07-01 22:04:21
PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1].

Name	H-D-Phe-Pro-Arg-chloromethylketone
Synonyms	H-D-PHE-PRO-ARG-CHLOROMETHYLKETONE TRIFLUOROACETATE SALT L-Prolinamide, D-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl] phenylalanyl-prolyl-argininemethylchloride H2N-DPhe-Pro-g-CMK H-D-PHE-PRO-G-CMK TFA H-D-PHE-PRO-G-CHLOROMETHYLKETONE TRIFLUOROACETATE SALT //BP H-D-Phe-Pro-g-chloromethylketone H-D-PHE-PRO-G-CHLOROMETHYLKETONE TRIFLUOROACETATE SALT PPACK dihydrochloride, Thrombin inhibitor H-D-PHE-PRO-ARG-CMK TFA D-Phe-Pro-g-CMK.TFA phenylalanyl-prolyl-gininemethylchloride H-D-Phe-Pro-g-CMK D-Phe-pro-g CH2Cl

Description	PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> PAI-1 Research Areas >> Cardiovascular Disease
References	[1]. Mohler MA, et, al. D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy. Thromb Haemost. 1986 Oct 21;56(2):160-4.