H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt

Modify Date: 2024-01-10 19:08:40

H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt structure	Common Name	H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt
	CAS Number	71142-71-7	Molecular Weight	450.96
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₃₁ClN₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt

PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1].

Name	H-D-Phe-Pro-Arg-chloromethylketone
Synonym	More Synonyms

Description	PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> PAI-1 Research Areas >> Cardiovascular Disease
References	[1]. Mohler MA, et, al. D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy. Thromb Haemost. 1986 Oct 21;56(2):160-4.