H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt

Modify Date: 2025-09-06 11:05:19

H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt Structure
H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt structure
 Common Name H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt
CAS Number 71142-71-7 Molecular Weight 450.96
Density N/A Boiling Point N/A
Molecular Formula C21H31ClN6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt


PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1].

 Names

Name H-D-Phe-Pro-Arg-chloromethylketone
Synonym More Synonyms

  Biological Activity

Description PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1].
Related Catalog
References

[1]. Mohler MA, et, al. D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy. Thromb Haemost. 1986 Oct 21;56(2):160-4.  

 Chemical & Physical Properties

Molecular Formula C21H31ClN6O3
Molecular Weight 450.96
Exact Mass 466.21000
PSA 163.63000
LogP 2.25500
Storage condition -15°C

 Synonyms

H-D-PHE-PRO-ARG-CHLOROMETHYLKETONE TRIFLUOROACETATE SALT
phenylalanyl-prolyl-argininemethylchloride
H-D-PHE-PRO-ARG-CMK TFA
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Chemsrc provides CAS#:71142-71-7 MSDS, density, melting point, boiling point, structure, etc. Its name is H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt>> amp version: H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt

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