142103-12-6

142103-12-6 structure

Name: 5-Me-3’-dU-2’-phosphoramidite
Chemical Name: 3'-dt cep
CAS Number: 142103-12-6
Molecular Formula: C₄₀H₄₉N₄O₈P
Molecular Weight: 744.81
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-10-06 09:04:33
Modify Date: 2024-01-09 17:05:07
5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	3'-dt cep
Synonyms	5-METHYL-3'-DU CEP 3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite

Description	5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

124482-92-4

143653-61-6

~64%

142103-12-6

Literature: Rizzo; Dougherty; Breslow Tetrahedron Letters, 1992 , vol. 33, # 29 p. 4129 - 4132

102691-36-1

143653-61-6

~80%

142103-12-6

Literature: Kumar, Anil; Katti, Seturam B.; Madhusudanan, Kunnath P. Nucleosides and Nucleotides, 1997 , vol. 16, # 1-2 p. 11 - 22

4613-71-2

142103-12-6

Literature: Rizzo; Dougherty; Breslow Tetrahedron Letters, 1992 , vol. 33, # 29 p. 4129 - 4132

143653-60-5

142103-12-6

Literature: Rizzo; Dougherty; Breslow Tetrahedron Letters, 1992 , vol. 33, # 29 p. 4129 - 4132

7288-28-0

142103-12-6

Literature: Rizzo; Dougherty; Breslow Tetrahedron Letters, 1992 , vol. 33, # 29 p. 4129 - 4132

Precursor 4
102691-36-1 4613-71-2 143653-60-5 7288-28-0
DownStream 0