5-Me-3’-dU-2’-phosphoramidite
5-Me-3’-dU-2’-phosphoramidite structure
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Common Name | 5-Me-3’-dU-2’-phosphoramidite | ||
|---|---|---|---|---|
| CAS Number | 142103-12-6 | Molecular Weight | 744.81 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C40H49N4O8P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 5-Me-3’-dU-2’-phosphoramidite5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 3'-dt cep |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C40H49N4O8P |
|---|---|
| Molecular Weight | 744.81 |
| Exact Mass | 744.32900 |
| PSA | 150.86000 |
| LogP | 6.81958 |
| InChIKey | GYSQEEMWSGWZLC-SXIXUTRBSA-N |
| SMILES | COc1ccc(C(OCC2CC(OP(OCCC#N)N(C(C)C)C(C)C)C(n3cc(C)c(=O)[nH]c3=O)O2)(c2ccccc2)c2ccc(OC)cc2)cc1 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~64%
5-Me-3’-dU-2’-p... CAS#:142103-12-6 |
| Literature: Rizzo; Dougherty; Breslow Tetrahedron Letters, 1992 , vol. 33, # 29 p. 4129 - 4132 |
|
~80%
5-Me-3’-dU-2’-p... CAS#:142103-12-6 |
| Literature: Kumar, Anil; Katti, Seturam B.; Madhusudanan, Kunnath P. Nucleosides and Nucleotides, 1997 , vol. 16, # 1-2 p. 11 - 22 |
|
~%
5-Me-3’-dU-2’-p... CAS#:142103-12-6 |
| Literature: Rizzo; Dougherty; Breslow Tetrahedron Letters, 1992 , vol. 33, # 29 p. 4129 - 4132 |
|
~%
5-Me-3’-dU-2’-p... CAS#:142103-12-6 |
| Literature: Rizzo; Dougherty; Breslow Tetrahedron Letters, 1992 , vol. 33, # 29 p. 4129 - 4132 |
|
~%
5-Me-3’-dU-2’-p... CAS#:142103-12-6 |
| Literature: Rizzo; Dougherty; Breslow Tetrahedron Letters, 1992 , vol. 33, # 29 p. 4129 - 4132 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
|---|---|
| DownStream 0 | |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 5-METHYL-3'-DU CEP |
| 3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of 3'-dt cep? |
| A: Main uses of 3'-dt cep: 5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Q: What is the molecular formula of 3'-dt cep? |
| A: Molecular formula of 3'-dt cep is C40H49N4O8P. |
| Q: What is the CAS number of 3'-dt cep? |
| A: CAS number of 3'-dt cep is 142103-12-6. |
| Q: What English synonyms does 3'-dt cep have? |
| A: English synonyms of 3'-dt cep: 5-METHYL-3'-DU CEP, 3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite. |
| Q: What are the upstream materials of 3'-dt cep? |
| A: Related upstream materials(CAS) of 3'-dt cep: 102691-36-1;4613-71-2;143653-60-5;7288-28-0. |
| Q: What is the molecular weight of 3'-dt cep? |
| A: Molecular weight of 3'-dt cep is 744.81. |
| Q: What is the English name of 3'-dt cep? |
| A: The English name of 3'-dt cep is 3'-dt cep. |
| Q: What is the InChIKey of 3'-dt cep? |
| A: InChIKey of 3'-dt cep is GYSQEEMWSGWZLC-SXIXUTRBSA-N. |
| Q: What is the polar surface area (PSA) of 3'-dt cep? |
| A: Polar surface area (PSA) of 3'-dt cep is 150.86000. |
| Q: What is the LogP of 3'-dt cep? |
| A: LogP of 3'-dt cep is 6.81958. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |