m-PEG3-OH

Modify Date: 2026-06-30 18:28:47

m-PEG3-OH structure	Common Name	m-PEG3-OH
	CAS Number	112-35-6	Molecular Weight	164.199
	Density	1.0±0.1 g/cm3	Boiling Point	233.9±20.0 °C at 760 mmHg
	Molecular Formula	C₇H₁₆O₄	Melting Point	-44ºC
	MSDS	Chinese USA	Flash Point	95.3±21.8 °C

Use of m-PEG3-OH

m-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	triethylene glycol monomethyl ether
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	m-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.0±0.1 g/cm3
Boiling Point	233.9±20.0 °C at 760 mmHg
Melting Point	-44ºC
Molecular Formula	C₇H₁₆O₄
Molecular Weight	164.199
Flash Point	95.3±21.8 °C
Exact Mass	164.104858
PSA	47.92000
LogP	-1.51
Vapour density	5.66 (vs air)
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.427
InChIKey	JLGLQAWTXXGVEM-UHFFFAOYSA-N
SMILES	COCCOCCOCCO

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

m-PEG3-OH MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KL6390000

CHEMICAL NAME :: Ethanol, 2-(2-(2-methoxyethoxy)ethoxy)-

CAS REGISTRY NUMBER :: 112-35-6

BEILSTEIN REFERENCE NO. :: 1700198

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C7-H16-O4

MOLECULAR WEIGHT :: 164.23

WISWESSER LINE NOTATION :: Q2O2O2O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,634,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,634,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11300 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 7100 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0892 No. of Facilities: 13261 (estimated) No. of Industries: 85 No. of Occupations: 32 No. of Employees: 80404 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0892 No. of Facilities: 2416 (estimated) No. of Industries: 22 No. of Occupations: 29 No. of Employees: 18956 (estimated) No. of Female Employees: 9842 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xi
Safety Phrases	S24/25-S22
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	KL6390000
HS Code	2909499000

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:620-24-6 3-Hydroxybenzyl... CAS#:249508-40-5 triethylene gly... CAS#:77-78-1 Dimethyl sulfate CAS#:112-27-6 Triethylene glycol
CAS#:16024-58-1 [2-(2-Methoxyet... CAS#:75-21-8 ETHYLENE OXIDE CAS#:67-56-1 Methanol CAS#:55489-58-2 2-{2-[2-(Benzyl...
CAS#:74-88-4 methyl iodide CAS#:81194-71-0 12,12-diphenyl-...
DownStream 10
CAS#:146395-16-6 2-[2-[2-[2-[2-(... CAS#:184709-01-1 2-[2-[2-(2-meth... CAS#:19685-21-3 2,5,8,11-tetrao... CAS#:18854-48-3 3-(2-Methoxyeth...
CAS#:1297518-94-5 CAS#:2387-23-7 1,3-Dicyclohexylurea CAS#:250608-58-3 1,4-diiodo-2,5-... CAS#:26256-87-1 TRI(ETHYLENE GL...
CAS#:24493-59-2 METHYLTRIGLYCOL... CAS#:25990-94-7 2,5,8,11,14,17,...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Core-shell polymer nanoparticles for prevention of GSH drug detoxification and cisplatin delivery to breast cancer cells.

Nanoscale 7 , 17964-79, (2015)

Platinum drug delivery against the detoxification of cytoplasmic thiols is urgently required for achieving efficacy in breast cancer treatment that is over expressed by glutathione (GSH, thiol-oligope...

Chemical modification of neamine.

Oncogene 21(28) , 4462-70, (2002)

The aminocyclitol antibiotic neamine has been modified chemically by removing one or two hydroxyl groups from the 2-deoxystreptamine moiety to give 5- and 6- deoxyneamines (5 and 10), as well as 5,6-d...

Synthesis of uniform cyclodextrin thioethers to transport hydrophobic drugs.

Beilstein J. Org. Chem. 10 , 2920-2927, (2014)

Methyl and ethyl thioether groups were introduced at all primary positions of α-, β-, and γ-cyclodextrin by nucleophilic displacement reactions starting from the corresponding per-(6-deoxy-6-bromo)cyc...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: Adrenergic beta2 receptor (ADRB2) small molecule agonists, cell-based qHTS assay
Source: 824
External Id: ADRB2293

Name: Adrenergic beta2 receptor (ADRB2) small molecule antagonists, cell-based qHTS assay
Source: 824
External Id: ADRB2713

Total 209, Current Page 1 of 21

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

UNII-DN0P4Q4I16

Triethylene glycol monomethyl ether

3,6,9-Trioxa-1-decanol

Triglycol monomethyl ether

2-(2-(2-Methoxyethoxy)ethoxy)ethanol

Methoxytriglycol

triethylene glycol methyl ether

Methoxytriethylene glycol

2-[2-(2-Methoxyethoxy)ethoxy]ethanol

Methyltrioxitol

Methyl Triglycol

Methyltriglycol

MFCD00002875

Methyl triethylene glycol

EINECS 203-962-1

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the molecular formula of triethylene glycol monomethyl ether?

A: Molecular formula of triethylene glycol monomethyl ether is C7H16O4.

Q: What is the English name of triethylene glycol monomethyl ether?

A: The English name of triethylene glycol monomethyl ether is triethylene glycol monomethyl ether.

Q: What are the uses of triethylene glycol monomethyl ether?

A: Main uses of triethylene glycol monomethyl ether: m-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Q: What English synonyms does triethylene glycol monomethyl ether have?

A: English synonyms of triethylene glycol monomethyl ether: UNII-DN0P4Q4I16, Triethylene glycol monomethyl ether, 3,6,9-Trioxa-1-decanol, Triglycol monomethyl ether, 2-(2-(2-Methoxyethoxy)ethoxy)ethanol, Methoxytriglycol, triethylene glycol methyl ether, Methoxytriethylene glycol, 2-[2-(2-Methoxyethoxy)ethoxy]ethanol, Methyltrioxitol, Methyl Triglycol, Methyltriglycol, MFCD00002875, Methyl triethylene glycol, EINECS 203-962-1.

Q: What is the melting point of triethylene glycol monomethyl ether?

A: Melting point of triethylene glycol monomethyl ether is -44ºC.

Q: What are the downstream products of triethylene glycol monomethyl ether?

A: Related downstream products(CAS) of triethylene glycol monomethyl ether: 146395-16-6;184709-01-1;19685-21-3;18854-48-3;1297518-94-5;2387-23-7;250608-58-3;26256-87-1;24493-59-2;25990-94-7.

Q: What is the polar surface area (PSA) of triethylene glycol monomethyl ether?

A: Polar surface area (PSA) of triethylene glycol monomethyl ether is 47.92000.

Q: What is the CAS number of triethylene glycol monomethyl ether?

A: CAS number of triethylene glycol monomethyl ether is 112-35-6.

Q: What are the upstream materials of triethylene glycol monomethyl ether?

A: Related upstream materials(CAS) of triethylene glycol monomethyl ether: 620-24-6;249508-40-5;77-78-1;112-27-6;16024-58-1;75-21-8;67-56-1;55489-58-2;74-88-4;81194-71-0.

Q: What is the SMILES notation of triethylene glycol monomethyl ether?

A: SMILES notation of triethylene glycol monomethyl ether is COCCOCCOCCO.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Zhongshan Xingrui Chemical Co. , Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: m-PEG3-OH
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Triethylene glycol monomethyl ether suppliers in China
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: m-PEG3-OH
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.