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1166-52-5

1166-52-5 structure
1166-52-5 structure
  • Name: Dodecyl gallate
  • Chemical Name: Dodecyl gallate
  • CAS Number: 1166-52-5
  • Molecular Formula: C19H30O5
  • Molecular Weight: 338.439
  • Catalog: Chemical reagent Organic reagent Ester Other ester compounds
  • Create Date: 2018-07-11 18:31:38
  • Modify Date: 2026-07-03 18:42:28
  • Dodecyl gallate (Lauryl gallate) has been widely used as an antioxidant in food manufacturing, as well as in the pharmaceutical and cosmetic industries. Dodecyl gallate also is active against a highly relevant animal virus such as African swine fever virus (ASFV)[1].
Name Dodecyl gallate
Synonyms Indole-51-cboxaldehyde
Lauryl 3,4,5-trihydroxybenzoate
E312
Dodecyl gallate Solution in Acetonitrile, 1000μg/mL
lauryl 3,4,5-trihydroxybenzoate
Nordihydroguaietic acid Solution, 1000ppm
Dodecyl Gallate in Acetonitrile
GALLIC ACID DODECYL ESTER
auryl gallate
Lauryl Gallate (Dodecyl Gallate)
3,4,5-TRIHYDROXYBENZOIC ACID DODECYL ESTER
3mg/kg
DODECYL 3,4,5-TRIHYDROXYBENZOATE FOR SYN
dodecylesterkyselinygallove
MFCD00002195
Gallicacid,dodecylester(6CI,8CI)
Gallic acid, lauryl ester
Gallic acid, dodecyl ester (8CI)
Benzoicacid,3,4,5-trihydroxy-,dodecylester
Lauryl gallate antioxidant, >= (HPLC)
Progallin LA
GALLIC ACID N-DODECYL ESTER
DODECYL GALLATE( DODECYL 3,4,5-TRIHYDROXYBENZOATE)
N-DODECYL GALLATE
Dodecyl gallate, synthesis ade
Nipagallin LA
dodecyl3,4,5
n-dodecyl 3,4,5-trihydroxybenzoate
3,4,5-trihydroxy-benzoicacidodecylester
Dodecyl gallate CRS
Lauryl gallate
progallinla
nipagallinla
DODECYL GALLATE
Gallic acid n-dodecyl ester
Gallic Acid Lauryl Ester
n-dodecyl gallate
3,4,5-trihydroxy-benzoic acid dodecyl ester
Gallic Acid Dodecyl Ester Gallic Acid Lauryl Ester Lauryl Gallate
Dodecylester kyseliny gallove
LAURYL GALLATE
Benzoic acid, 3,4,5-trihydroxy-, dodecyl ester
Dodecyl gallate 1-5 Lauryl gallate
Dodecyl 3,4,5-trihydroxybenzoate
Dodocyl gallate
Dodecyl 3,4,5-trihydroxybenzoate 1-5 Dodecyl gallate
GALLIC ACID LAURYL ESTER
Gallic acid, dodecyl ester
Gallic Acid Dodecyl Ester
EINECS 214-620-6
Description Dodecyl gallate (Lauryl gallate) has been widely used as an antioxidant in food manufacturing, as well as in the pharmaceutical and cosmetic industries. Dodecyl gallate also is active against a highly relevant animal virus such as African swine fever virus (ASFV)[1].
Related Catalog
In Vitro Dodecyl gallate (Lauryl gallate) is an ester derivative of gallic acid, a natural plant phenolic compound. Dodecyl gallate (Lauryl gallate) protects cells from oxidative stress, in a process associated with radical scavenging, inhibition of enzymes involved in lipid peroxidation, and increasing expression of antioxidant genes. Due to its hydrophobic properties, Dodecyl gallate can disrupt biomembranes and cause protein inactivation[1].
References

[1]. Patricia de León, et al. Inhibition of Porcine Viruses by Different Cell-Targeted Antiviral Drugs. Front Microbiol. 2019 Aug 14;10:1853.
Density 1.1±0.1 g/cm3
Boiling Point 521.7±45.0 °C at 760 mmHg
Melting Point 94-97 °C(lit.)
Molecular Formula C19H30O5
Molecular Weight 338.439
Flash Point 180.3±22.2 °C
Exact Mass 338.209320
PSA 86.99000
LogP 7.38
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.535
Storage condition 0-6°C
Water Solubility practically insoluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DH9100000
CHEMICAL NAME :
Benzoic acid, 3,4,5-trihydroxy-, dodecyl ester
CAS REGISTRY NUMBER :
1166-52-5
BEILSTEIN REFERENCE NO. :
2701981
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C19-H30-O5
MOLECULAR WEIGHT :
338.49
WISWESSER LINE NOTATION :
QR BQ CQ EVO12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. Volume(issue)/page/year: 38A,22,1965 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
135 gm/kg/32W-C
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JAOCA7 Journal of the American Oil Chemists' Society. (Champaign, IL) V.24-56, 1947-79. Volume(issue)/page/year: 28,304,1951
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
75 gm/kg/10D-C
TOXIC EFFECTS :
Behavioral - food intake (animal) Related to Chronic Data - death
REFERENCE :
JAOCA7 Journal of the American Oil Chemists' Society. (Champaign, IL) V.24-56, 1947-79. Volume(issue)/page/year: 28,304,1951
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H317
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R43
Safety Phrases S24-S37
RIDADR 3335
WGK Germany 1
RTECS DH9100000
HS Code 29182950
112-53-8 structure

112-53-8

149-91-7 structure

149-91-7

~73%

1166-52-5 structure

1166-52-5

Literature: Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75
1063201-08-0 structure

1063201-08-0

~65%

1166-52-5 structure

1166-52-5

Literature: Dodo, Kosuke; Minato, Taro; Noguchi-Yachide, Tomomi; Suganuma, Masami; Hashimoto, Yuichi Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 17 p. 7975 - 7982
112-53-8 structure

112-53-8

35388-10-4 structure

35388-10-4

~%

1166-52-5 structure

1166-52-5

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 70, p. 277,281
HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%
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