220991-20-8

220991-20-8 structure

Name: Lumiracoxib
Chemical Name: lumiracoxib
CAS Number: 220991-20-8
Molecular Formula: C₁₅H₁₃ClFNO₂
Molecular Weight: 293.721
Catalog: Biochemical Inhibitor Neuronal Signaling COX inhibitor
Create Date: 2018-08-23 07:01:28
Modify Date: 2025-08-27 18:02:02
Lumiracoxib, also known as CGS 35189 and COX 189, is a COX-2 selective inhibitor non-steroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige. Since its original approval, lumiracoxib has been withdrawn from the market in several countries, mostly due to its potential for causing liver failure (sometimes requiring liver transplantation). It has never been approved for use in the United States.

Name	lumiracoxib
Synonyms	2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-benzeneacetic acid Prexige (Novartis) 2-(2-((2-chloro-6-fluorophenyl)amino)-5-methylphenyl)acetic acid {2-[(2-Chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid Prexige COX189 5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid Joicela Benzeneacetic acid, 2-[(2-chloro-6-fluorophenyl)amino]-5-methyl- (2-((2-chloro-6-fluorophenyl)-amino)-5-methylphenyl)-acetic acid Lumiracoxib [14C]-Lumiracoxib 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid Lumiracoxib [USAN:INN]