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4437-01-8

4437-01-8 structure
4437-01-8 structure
  • Name: m-PEG7-alcohol
  • Chemical Name: 2,5,8,11,14,17,20-Heptaoxadocosan-22-ol
  • CAS Number: 4437-01-8
  • Molecular Formula: C15H32O8
  • Molecular Weight: 340.410
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-04-17 08:00:00
  • Modify Date: 2024-01-03 17:11:05
  • m-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Name 2,5,8,11,14,17,20-Heptaoxadocosan-22-ol
Synonyms 2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
MFCD06201006
Heptaethylene Glycol MonoMethyl Ether
2,5,8,11,14,17,20-Heptaoxadocosan-22-ol
Description m-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Density 1.1±0.1 g/cm3
Boiling Point 416.0±40.0 °C at 760 mmHg
Molecular Formula C15H32O8
Molecular Weight 340.410
Flash Point 205.4±27.3 °C
Exact Mass 340.209717
PSA 84.84000
LogP -2.95
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.449
WGK Germany 3
HS Code 2909499000
HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Chemsrc provides CAS#:4437-01-8 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 4437-01-8 | Chemsrc address: https://m.chemsrc.com/en/baike/831711.html

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