74654-05-0
74654-05-0 structure
- Name: m-PEG3-OMs
- Chemical Name: methanesulfonic acid,2-[2-(2-methoxyethoxy)ethoxy]ethanol
- CAS Number: 74654-05-0
- Molecular Formula: C8H18O6S
- Molecular Weight: 260.30500
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-07-04 09:07:57
- Modify Date: 2024-01-12 17:28:59
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m-PEG3-OMs is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | methanesulfonic acid,2-[2-(2-methoxyethoxy)ethoxy]ethanol |
|---|---|
| Synonyms | triethyleneglycol monomethyl ether methanesulfonate |
| Description | m-PEG3-OMs is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C8H18O6S |
|---|---|
| Molecular Weight | 260.30500 |
| Exact Mass | 260.09300 |
| PSA | 110.67000 |
| LogP | 0.24310 |
| Storage condition | -20°C |
|
~97%
74654-05-0 |
| Literature: Fukase, Koichi; Takashina, Mamoru; Hori, Yumiko; Tanaka, Daizo; Tanaka, Katsunori; Kusumoto, Shoichi Synlett, 2005 , # 15 art. no. U21305ST, p. 2342 - 2346 |
| Precursor 2 | |
|---|---|
| DownStream 5 | |
