Name | Flupenthixol dihydrochloride |
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Synonyms |
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)thioxanthen-9-ylidene)propyl)-, dihydrochloride (8CI)
(Z)-4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol dihydrochloride 1-Piperazineethanol, 4-[3-[2- (trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, dihydrochloride cis-Flupentixol Hydrochloride FUPENTIXOL DIHYDROCHLORIDE FLUPENTIXOL DIHYDROCHLORIDE 4-[3-[(3Z)-2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol Hydrochloride a-Flupenthixol Hydrochloride Zimelidine dihydrochloride Fupentixol HCl 4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride (Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride 2-(4-{(3E)-3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}-1-piperazinyl)ethanol dihydrochloride 2-(4-{(3E)-3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol dihydrochloride Metamin 1-Piperazineethanol, 4-[(3E)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, hydrochloride (1:2) Thioxanthene, 9-(3-(4-(2-hydroxyethyl)piperazinyl)propylidene)-2-trifluoromethyl-, dihydrochloride Fluanxol dihydrochloride 1-Piperazineethanol, 4-[(3Z)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, hydrochloride (1:2) 2-(4-{(3Z)-3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}-1-piperazinyl)ethanol dihydrochloride 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-, dihydrochloride (9CI) CIS-(Z)-FLUPENTHIXOL DIHYDROCHLORIDE ANT IPSYCHOTIC,NEUROL 1-Piperazineethanol, 4-[3-[2- (trifluoromethyl)thioxanthen-9-ylidene]propyl]-, dihydrochloride 2-(4-{(3Z)-3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol dihydrochloride flupentixolhydrochloride fx703 cis-(Z)-Flupentixol Dihydrochloride |
Description | cis-(Z)-Flupentixol dihydrochloride is a potent and selective DA D1/D2 receptor antagonist, with Ki values of 0.38 nM and 7 nM for D2 receptor and 5-HT2A, respectively[1][2]. |
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Related Catalog | |
Target |
D2 Receptor:0.38 nM (Ki) 5-HT2A Receptor:7 nM (Ki) |
In Vivo | cis-(Z)-Flupentixol (0.25, or 0.5 mg/kg, i.p.) pretreatment dose-dependently reduces cocaine-induced activity[1]. Animal Model: Rats[1]. Dosage: 0.125, 0.25, or 0.5 mg/kg. Administration: IP. Result: Reduced cocaine-induced activity. |
References |
Boiling Point | 554.7ºC at 760 mmHg |
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Melting Point | 194-202ºC |
Molecular Formula | C23H27Cl2F3N2OS |
Molecular Weight | 507.440 |
Flash Point | 289.3ºC |
Exact Mass | 506.117310 |
PSA | 52.01000 |
LogP | 6.08150 |
Appearance | white to off-white |
Storage condition | -20°C Freezer |
Water Solubility | H2O: soluble |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302 + H312 + H332 |
Precautionary Statements | P261-P280-P301 + P312 + P330 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R20/21/22 |
Safety Phrases | S36/37/39 |
RIDADR | UN 2811 |
RTECS | TL9900000 |
HS Code | 2942000000 |
HS Code | 2942000000 |
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