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Related CAS#:
18259-15-9 537-42-8
1318852-41-3 441351-32-2
959699-21-9 1224713-72-7

537-42-8

537-42-8 structure
537-42-8 structure
  • Name: pterostilbene
  • Chemical Name: pterostilbene
  • CAS Number: 537-42-8
  • Molecular Formula: C16H16O3
  • Molecular Weight: 256.296
  • Catalog: Biochemical Plant extracts
  • Create Date: 2018-04-22 08:00:00
  • Modify Date: 2024-01-02 13:45:59
  • Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].
Name pterostilbene
Synonyms 4-(3,5-Dimethoxystyryl)phenol
4-[(E)-2-(3,5-Diméthoxyphényl)éthènyl]phénol
Phenol, 4-(2-(3,5-dimethoxyphenyl)ethenyl)-, (E)-
3,5-Dimethoxy-4'-hydroxy-trans-stilbene
3',5'-Dimethoxy-4-stilbenol
4-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol
4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]phenol
(E)-4-(3,5-Dimethoxystyryl)phenol
trans-1-(3,5-Dimethoxyphenyl)-2-(4-hydroxyphenyl)ethylene
Pterostilbene
4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol
Phenol, 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-
Pterostilbene,Pterocarpus marsupium
(E)-pterostilbene
4-Stilbenol, 3',5'-dimethoxy-, (E)-
3,5-dimethoxy-4'-hydroxystilbene
4'-hydroxy-3,5-dimethoxystilbene
4'-Hydroxy-3,5-dimethoxy-trans-stilbene
Description Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].
Related Catalog
In Vitro Pterostilbene (0, 5, 25, 50, 100, 200 and 400 µM) shows inhibitory activity against the growth of HeLa cells, with IC50s of 101.2 µM and 65.9 µM at 24 and 48 hrs, respectively. Ipterostilbene (0, 25, 100 and 200 µM) also induces the apoptosis HeLa cells[2]. Pterostilbene (0.05, 0.1, 0.15 and 0.2 mM) has high anti-oxidant activity against DPPH, ABTS, hydroxyl, superoxide, hydrogen peroxide in a dose-dependent manner. Pterostilbene decreases lipid peroxides and hydroperoxides, reduces protein carbonyl groups and restores protein sulphydryl groups in response to damage by TBHP and As-Fe2+. Pterostilbene also inhibits single strand breaks in pBR322[4].
In Vivo Pterostilbene (30 mg/kg daily, p.o. for 21 days) inhibits reactive oxygen species production in the animal model of inflammation[3].
References

[1]. McCormack D, et al. A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev. 2013;2013:575482.

[2]. Hong Bin W, et al. Pterostilbene (3',5'-dimethoxy-resveratrol) exerts potent antitumor effects in HeLa human cervical cancer cells via disruption of mitochondrial membrane potential, apoptosis induction and targeting m-TOR/PI3K/Akt signalling pathway. J BUON. 2018 Sep-Oct;23(5):1384-1389.

[3]. Perecko T, et al. The effects of pterostilbene on neutrophil activity in experimental model of arthritis. Biomed Res Int. 2013;2013:106041.

[4]. Acharya JD, et al. Protective effect of Pterostilbene against free radical mediated oxidative damage. BMC Complement Altern Med. 2013 Sep 26;13:238.
Density 1.2±0.1 g/cm3
Boiling Point 420.5±35.0 °C at 760 mmHg
Melting Point 89-92ºC
Molecular Formula C16H16O3
Molecular Weight 256.296
Flash Point 208.1±25.9 °C
Exact Mass 256.109955
PSA 38.69000
LogP 4.13
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.640
Storage condition 2-8°C
Water Solubility DMSO: >20mg/mL
Symbol GHS05 GHS09
GHS05, GHS09
Signal Word Danger
Hazard Statements H318-H411
Precautionary Statements P273-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R41;R51/53
Safety Phrases S26-S39-S61
RIDADR UN 3077
Packaging Group Ⅲ
Hazard Class 9.0
HS Code 2909500000
HS Code 2909500000
Summary 2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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title: CAS No. 537-42-8 | Chemsrc address: https://m.chemsrc.com/en/baike/832386.html

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