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56-86-0

56-86-0 structure
56-86-0 structure
  • Name: L-glutamic acid
  • Chemical Name: L-glutamic acid
  • CAS Number: 56-86-0
  • Molecular Formula: C5H9NO4
  • Molecular Weight: 147.129
  • Catalog: Biochemical Common amino acids and protein drugs
  • Create Date: 2018-02-07 08:00:00
  • Modify Date: 2026-06-30 19:24:31
  • (S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
Name L-glutamic acid
Synonyms Glusate
L-(+)Glutamicacid,Glu
(S)-2-AMINOGLUTIC ACID
1-Aminopropane-1,3-dicboxylic acid
1-aminopropane-1,3-dicboxylicacid
L-Glutamic acid,(S)-2-Aminopentanedioic acid, Glu
H-GLU-OH
GLU
L-Glutamicacid
ACIDUM GLUTAMICUM
GLUTACID
L-GLUTAMIC ACIDRESECH ADE
L-GLUTAMIC ACID FCC
(S)-2-Aminopentanedioic acid, Acidum glutamicum, Glu
L-α-Aminoglutic acid
GLUTAMIC ACID BASE
L-GlutamicAcid
L-GLUTAMIC ACID, L-GLUTAMIC ACID, L-GLUTAMIC ACID, L-GLUTAMIC ACID
L-Glutamic acid,(S)-2-Aminopentanedioic acid, Acidum glutamicum, Glu
L-Glutanmic
L-GLUTAMIC ACID, REAGENTPLUS TM, >=
L-Glutamic acid (S)-2-Aminopentanedioic acid
L-Glutamic Acid Impurity
Glutamidex
Glutamic Acid
Glutamicol
EINECS 200-293-7
L-Glutamcacid
MFCD00002634
alpha-Glutamic acid
L-Glutamic acid, extra , Ph Eur, FCC
L-Glutaminic acid
H-L-GLU-OH
L-GLU
Pemetrexed Impurity M
D-Glutamiensuur
glutaminicacid
l-glutaminicacid
(S)-(+)-GLUTAMIC ACID
(S)-2-Aminopentanedioic acid, Glu
L-GLUTAMIC ACID, FREE ACID
[S]-2-AMINOPENTANEDIOIC ACID
L(+)-GlutaMic acid, R
(S)-1-AMINOPROPANE-1,3-DICBOXYLIC ACID
Pemetrexed Impurity 1
L-Glutamic acid
(2S)-2-Aminopentanedioic acid
Glutaminol
GLUTAMIC ACID, L
ALPHA-AMINOGLUTIC ACID
(S)-Glutamic acid
L(+)-GLUTAMIC ACID EXTRA DAB FCC
(S)-GLUTAMIC ACID
L-GLUTAMIC ACID extrapure
alpha-glutamicacid
Glutaminic acid
Asptic Acid Impurity 7
L(+)-Glutamic acid, Ultra ,(NT)
Glutamine ImpuritⅠ：L-Glutamic acid
Aciglut
Pentanedioic acid, 2-amino-, (S)
glutamic
L-GLUTAMIC ACID, PH EUR
Glutaton
Description (S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
Related Catalog
Target

Human Endogenous Metabolite

DA

References

[1]. Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.
Density 1.4±0.1 g/cm3
Boiling Point 333.8±32.0 °C at 760 mmHg
Melting Point 205 °C (dec.)(lit.)
Molecular Formula C5H9NO4
Molecular Weight 147.129
Flash Point 155.7±25.1 °C
Exact Mass 147.053162
PSA 100.62000
LogP -1.43
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.522
Water Solubility 7.5 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ9700000
CHEMICAL NAME :
Glutamic acid, L-
CAS REGISTRY NUMBER :
56-86-0
LAST UPDATED :
199706
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C5-H9-N-O4
MOLECULAR WEIGHT :
147.15
WISWESSER LINE NOTATION :
QVYZ2VQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
71 mg/kg
TOXIC EFFECTS :
Behavioral - headache
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human
DOSE/DURATION :
117 mg/kg
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>30 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80420 No. of Facilities: 446 (estimated) No. of Industries: 6 No. of Occupations: 13 No. of Employees: 10592 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80420 No. of Facilities: 915 (estimated) No. of Industries: 10 No. of Occupations: 27 No. of Employees: 11240 (estimated) No. of Female Employees: 5754 (estimated)
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS LZ9700000
HS Code 2922421000
HS Code 2922421000
Summary HS: 2922421000. (s)-2-aminopentanedioic acid. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:ab(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tarrif:10.0%. general tariff:90.0%
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