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China
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China
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Flavomycin
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Henan Tianfu Chemical Co., Ltd.
China
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11015-37-5

11015-37-5 structure

11015-37-5 structure

Name: Bambermycin
Chemical Name: bambermycin
CAS Number: 11015-37-5
Molecular Formula: C₆₉H₁₀₇N₄O₃₅P
Molecular Weight: 1582.583
Catalog: API Feed drug additive
Create Date: 2018-06-15 19:32:56
Modify Date: 2024-01-02 22:47:46
Moenomycin complex is a potent transglycosylase inhibitor. Moenomycin complex inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs)[1].

Name	bambermycin
Synonyms	(2R)-3-{[{[(2R,3R,4R,5S,6S)-3-{[(2S,3R,4R,5S,6R)-3-Acetamido-5-{[(2S,3R,4R,5S,6R)-3-acetamido-4-hydroxy-6-methyl-5-({(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)carbamoyl]tetrahydro-2H-pyran-2-yl}oxy)tetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-6-carbamoyl-4-(carbamoyloxy)-5-hydroxy-5-methyltetrah Moenomycine MOENOMYCIN menomycin Bambermycine BAMBERMYCIN BAMBERMYCINS flavophospholipol Flavomycin moenomycin a

Description	Moenomycin complex is a potent transglycosylase inhibitor. Moenomycin complex inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Transglycosylase[1]
References	[1]. Cheng TJ, et al. Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):431-6.

Density	1.5±0.1 g/cm3
Molecular Formula	C₆₉H₁₀₇N₄O₃₅P
Molecular Weight	1582.583
Exact Mass	1581.661377
PSA	611.69000
LogP	4.81
Index of Refraction	1.615
Storage condition	0-6°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QA3020000

CHEMICAL NAME :: Moenomycin

CAS REGISTRY NUMBER :: 11015-37-5

LAST UPDATED :: 198910

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 1,740,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 1,740,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Behavioral - wakefulness Behavioral - somnolence (general depressed activity)

REFERENCE :: AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI) 1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year: -,743,1965

Hazard Statements	H413
Risk Phrases	53
RIDADR	UN 3077 9 / PGIII
RTECS	QA3020000