469-36-3

469-36-3 structure

Name: 24-Methylene cycloartanyl ferulate
Chemical Name: oryzanol
CAS Number: 469-36-3
Molecular Formula: C₄₁H₆₀O₄
Molecular Weight: 616.913
Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
Create Date: 2018-09-25 18:01:09
Modify Date: 2024-01-02 11:48:11
24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM)[1].

Name	oryzanol
Synonyms	24-Methylenecycloartanyl Ferulate 3-O-feruloylquinic acid Oryzanol C 3-Feruloylchinasaeure 3-feruloylquinic acid 3-O-ferulyl-24-methylenecycloartanol 5-O-feruloyl quinic acid 24-methylenecycloartanol ferulate 24-methylcycloartanyl ferulate 24-methylene cycloartanyl ferulate (3β,9β)-24-Methylene-9,19-cyclolanostan-3-yl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate (3β,9β)-24-methylidene-9,19-cyclolanostan-3-yl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 24-methylenecycloartanol trans-ferulate 2-propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (3β,9β)-24-methylene-9,19-cyclolanostan-3-yl ester, (2E)- 5-feruloylquinic acid

Description	24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> Akt
Target	Akt1:33.3 μM (EC50)
References	[1]. Heon Woong Kim, et al. 24-Methylenecycloartanyl ferulate, a major compound of γ-oryzanol, promotes parvin-beta expression through an interaction with peroxisome proliferator-activated receptor-gamma 2 in human breast cancer cells. Biochem Biophys Res Commun. 2015 Dec 25;468(4):574-9.