1668-85-5

1668-85-5 structure

Name: Epi-galantamine
Chemical Name: Epi Galanthamine
CAS Number: 1668-85-5
Molecular Formula: C₁₇H₂₁NO₃
Molecular Weight: 287.35400
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2018-09-11 13:16:26
Modify Date: 2024-01-13 17:17:13
Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45.7 μM[1][2][3].

Name	Epi Galanthamine
Synonyms	(-)-epigalanthamine

Description	Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45.7 μM[1][2][3].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	EC50: 45.7 μM (AChE)[1]
References	[1]. Thomsen T, et al. Stereoselectivity of cholinesterase inhibition by galanthamine and tolerance in humans. Eur J Clin Pharmacol. 1990;39(6):603-5. [2]. Berkov S, et al. Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts. Phytochem Anal. 2008 Sep-Oct;19(5):411-9. [3]. Maláková J, et al. High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 15;853(1-2):265-74.

Hazard Codes	T+

Precursor 0
DownStream 1
510-77-0