1668-85-5

1668-85-5 structure

Name: Epi-galantamine
Chemical Name: Epi Galanthamine
CAS Number: 1668-85-5
Molecular Formula: C₁₇H₂₁NO₃
Molecular Weight: 287.35400
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2018-09-11 13:16:26
Modify Date: 2026-07-17 12:39:58
Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45.7 μM[1][2][3].

Name	Epi Galanthamine
Synonyms	(4aS,6S,8aS)-3-methoxy-11-methyl-5,6,9,10,11,12- hexahydro-4aH-benzofuro[3a,3,2-ef]benzazin-6-ol (-)-epigalanthamine I-GALANTHAMINE Galantamine hydrobromide Impurity B (4aS,6S,8aS)-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzofuro[3a,3,2-ef]benzazin-6-ol i-galantamine) 6H-Benzofuro[3a,3,2-ef]benzazin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, (4aS,6S,8aS) i-Galantamine Galantamine Impurity B i-Galantamine) i galantamine,inhibit,i-galantamine,alkaloid,Cholinesterase (ChE),igalantamine,Inhibitor,Diastereomer i-galantamine, 10 mM in DMSO (-)-igalanthamine 3-igalanthaMine i-GalantaMine (GalantaMine IMpurity B) (4aS,6S,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef]benzazin-6-ol Galanthamine Impurity B Galantamine impurity B (4aS,8aS)-3-methoxy-11-methyl-9,10,11,12- tetrahydro-4aH-benzofuro[3a,3,2-ef]benzazine hydrobromide Galantamine Impurity 2（Galantamine Impurity B） Galantamine hydrobromide Imp. B: (4aS,6S,8aS)-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH- benzofuro[3a,3,2-ef]benzazin-6-ol i-galantamine)

Description	Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45.7 μM[1][2][3].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	EC50: 45.7 μM (AChE)[1]
References	[1]. Thomsen T, et al. Stereoselectivity of cholinesterase inhibition by galanthamine and tolerance in humans. Eur J Clin Pharmacol. 1990;39(6):603-5. [2]. Berkov S, et al. Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts. Phytochem Anal. 2008 Sep-Oct;19(5):411-9. [3]. Maláková J, et al. High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 15;853(1-2):265-74.

Hazard Codes	T+

Precursor 0
DownStream 1
510-77-0