77544-68-4
77544-68-4 structure
- Name: Tos-PEG3
- Chemical Name: 2-[2-(2-Hydroxyethoxy)ethoxy]ethyl 4-methylbenzenesulfonate
- CAS Number: 77544-68-4
- Molecular Formula: C13H20O6S
- Molecular Weight: 304.35900
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-11-08 16:42:08
- Modify Date: 2026-07-01 19:16:23
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Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports[1].
| Name | 2-[2-(2-Hydroxyethoxy)ethoxy]ethyl 4-methylbenzenesulfonate |
|---|---|
| Synonyms |
Hydroxy-PEG3-Tos
p-toluenesulfonic acid 2-(2-(2-hydroxyethoxy)ethoxy)ethoxy ester Triethylene glycol p-toluenesulfonate 2-(2-(2-Hydroxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate PEG3-Tos Ethanol,2-[2-(2-hydroxyethoxy)ethoxy]-,1-(4-methylbenzenesulfonate) OH-PEG3-Tos 2,2'-[ethane-1,2-diylbis(oxy)]bis[ethanol] mono(4-methylbenzenesulfonate) Tos-PEG4-alcohol Tos-PEG3-alcohol Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate) Triethylene glycol monotosylate Tos-PEG4 HO(C2H4O)3Tos Tos-PEG3-OH/Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-methylbenzenesulfonate) PEG4-Tos 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate) HO-(CH2CH2O)3-Tos os-PEG3-alcohol HO-PEG3-OTS Ts(OCH2CH2)3OH Tos-PEG3-OH triethyleneglycol monotosylate toluene-4-sulfonic acid 2-[2-(2-hydroxy-ethoxy)ethoxy]ethyl ester |
| Description | Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports[1]. |
|---|---|
| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Density | 1.234±0.06 g/cm3 |
|---|---|
| Boiling Point | 460.0±35.0 °C |
| Molecular Formula | C13H20O6S |
| Molecular Weight | 304.35900 |
| Exact Mass | 304.09800 |
| PSA | 90.44000 |
| LogP | 1.80660 |
| HS Code | 2909499000 |
|---|
| Precursor 2 | |
|---|---|
| DownStream 10 | |
![2-[2-(2-Aminoethoxy)ethoxy]ethanol structure](https://image.chemsrc.com/caspic/352/6338-55-2.png)
![2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid structure](https://image.chemsrc.com/caspic/007/172531-37-2.png)
![2-[2-(2-fluoroethoxy)ethoxy]ethanol structure](https://image.chemsrc.com/caspic/227/373-45-5.png)
| HS Code | 2909499000 |
|---|---|
| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |