Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine inner salt, 1,4-butanedisulfonate
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Purity: 98.0%
Stocking Period: Inquiry
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200393-05-1

200393-05-1 structure

Name: Adenosylmethionine 1,4-butanedisulfonate
Chemical Name: (2S)-2-({[(2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-3-{[( 4-sulfobutyl)sulfonyl]oxy}tetrahydro-2-furanyl]methyl}amino)-4-(m ethylsulfanyl)butanoic acid (non-preferred name)
CAS Number: 200393-05-1
Molecular Formula: C₁₉H₃₀N₆O₁₀S₃
Molecular Weight: 598.67100
Catalog: Biochemical Amino acids and their derivatives Methionine derivatives
Create Date: 2018-09-17 12:43:08
Modify Date: 2024-01-05 18:28:11
S-Adenosyl-L-methionine (S-Adenosyl methionine) 1,4-butanedisulfonate is an orally active methyl group donor. S-Adenosyl-L-methionine 1,4-butanedisulfonate is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine 1,4-butanedisulfonate also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine 1,4-butanedisulfonate has the potential for, cancer, liver disease and osteoarthritis research[1][2][3].

Name	(2S)-2-({[(2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-3-{[( 4-sulfobutyl)sulfonyl]oxy}tetrahydro-2-furanyl]methyl}amino)-4-(m ethylsulfanyl)butanoic acid (non-preferred name)
Synonyms	Adenosylmethionine 1,4-butanedisulfonate

Description	S-Adenosyl-L-methionine (S-Adenosyl methionine) 1,4-butanedisulfonate is an orally active methyl group donor. S-Adenosyl-L-methionine 1,4-butanedisulfonate is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine 1,4-butanedisulfonate also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine 1,4-butanedisulfonate has the potential for, cancer, liver disease and osteoarthritis research[1][2][3].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. G M Bressa. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14. [2]. Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 26;5:6. [3]. Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct;92(4):1515-42. [4]. Mosca L, et al. Effects of S‑adenosyl‑L‑methionine on the invasion and migration of head and neck squamous cancer cells and analysis of the underlying mechanisms. Int J Oncol. 2020 May;56(5):1212-1224. [5]. Ham MS, et al. S-adenosyl methionine specifically protects the anticancer effect of 5-FU via DNMTs expression in human A549 lung cancer cells. Mol Clin Oncol. 2013 Mar;1(2):373-378. [6]. Ornoy A, et al. S-adenosyl methionine prevents ASD like behaviors triggered by early postnatal valproic acid exposure in very young mice. Neurotoxicol Teratol. 2019 Jan-Feb;71:64-74. [7]. Dhediya RM, et al. Evaluation of antiepileptic effect of S-adenosyl methionine and its role in memory impairment in pentylenetetrazole-induced kindling model in rats. Epilepsy Behav. 2016 Aug;61:153-157.

Molecular Formula	C₁₉H₃₀N₆O₁₀S₃
Molecular Weight	598.67100
Exact Mass	598.11900
PSA	288.21000
LogP	1.97940

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