56684-87-8

56684-87-8 structure

Name: Batatasin III
Chemical Name: 3-Methoxy-5-[2-(3-methoxyphenyl)ethyl]phenol
CAS Number: 56684-87-8
Molecular Formula: C₁₆H₁₈O₃
Molecular Weight: 258.31200
Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
Create Date: 2017-06-22 00:22:51
Modify Date: 2024-01-11 10:07:55
Batatasin III, a stilbenoid, inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition (EMT) and FAK-AKT Signals. Batatasin III has anti-cancer activities[1].

Name	3-Methoxy-5-[2-(3-methoxyphenyl)ethyl]phenol
Synonyms	3-Ethyl-1-<2-(3-indolyl)-ethyl>-piperidin 3-[2-(3-ethyl-piperidin-1-yl)-ethyl]-indole batatatsin III batatasin III 1-<2-(3-indolyl)ethyl>-3-ethylpiperidine 1H-Indole,3-[2-(3-ethyl-1-piperidinyl)ethyl] 3,3'-dihydroxy-5-methoxybibenzyl 3-[2-(3-hydroxyphenyl)ethyl]-5-methoxyphenol Batatasin Ⅲ

Description	Batatasin III, a stilbenoid, inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition (EMT) and FAK-AKT Signals. Batatasin III has anti-cancer activities[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FAK Signaling Pathways >> PI3K/Akt/mTOR >> Akt
Target	Akt
In Vitro	Batatasin III (25-100 μM; 48 h) exhibits anti-proliferative activity in H460 cells. Batatasin III at concentrations lower than 100 μM has no cytotoxic effects[1]. Batatasin III significantly suppresses EMT indicated by the decrease of N-cadherin and Vimentin, and up-regulation of E-cadherin[1].
References	[1]. Tatchakorn Pinkhien, et al. Batatasin III Inhibits Migration of Human Lung Cancer Cells by Suppressing Epithelial to Mesenchymal Transition and FAK-AKT Signals. Anticancer Res. 2017 Nov;37(11):6281-6289.

1700-37-4

58026-13-4

56684-87-8

Literature: Hashimoto,T. et al. Phytochemistry (Elsevier), 1974 , vol. 13, p. 2849 - 2852

Precursor 2
1700-37-4 58026-13-4
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