1217222-76-8

1217222-76-8 structure

1217222-76-8 structure

Name: Furazolidone-D4
Chemical Name: 4,4,5,5-tetradeuterio-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
CAS Number: 1217222-76-8
Molecular Formula: C₈H₃D₄N₃O₅
Molecular Weight: 229.18
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2018-05-10 08:00:00
Modify Date: 2024-01-08 20:35:50
Furazolidone-d4 is deuterium labeled Furazolidone.

Name	4,4,5,5-tetradeuterio-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
Synonyms	Furaxon-d4 Furazolidon-d4 Tikofuran-d4 Diafuron-d4 Giardil-d4 Furazolidone-d4 Trifurox-d4 Topazone-d4 Roptazol-d4 Furazol-d4

Description	Furazolidone-d4 is deuterium labeled Furazolidone.
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Jiang X, et al. A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia. PLoS One. 2013 Aug 9;8(8):e72335.

Molecular Formula	C₈H₃D₄N₃O₅
Molecular Weight	229.18
Exact Mass	229.06400
PSA	100.86000
LogP	1.43500

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H361
Precautionary Statements	P281
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn
Risk Phrases	62
Safety Phrases	36/37
RIDADR	NONH for all modes of transport