Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 7H-Pyrrolo(3,2-f)quinazoline-1,3-diamine, 7-((4-aminophenyl)methyl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

77681-42-6

77681-42-6 structure

Name	7-[(4-aminophenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine

Description	NSC309401 is an inhibitor of E. coli DHFR (IC50: 189 nM, KD: 14.57 nM)[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
Target	189 nM (E. coli DHFR)[1]
References	[1]. Srinivasan B, et al. Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors. FEBS J. 2015 May;282(10):1922-38.