284665-22-1

284665-22-1 structure

Name: butane-1,4-diaminium dichloride
Chemical Name: 1,1,2,2,3,3,4,4-octadeuteriobutane-1,4-diamine,dihydrochloride
CAS Number: 284665-22-1
Molecular Formula: C₄H₁₄Cl₂N₂
Molecular Weight: 161.073
Catalog: Research Areas Endocrinology
Create Date: 2018-03-16 08:00:00
Modify Date: 2024-01-09 18:10:22
1,4-Diaminobutane-d8 (dihydrochloride) is the deuterium labeled 1,4-Diaminobutane dihydrochloride[1]. 1,4-Diaminobutane (Putrescine) dihydrochloride is an endogenous metabolite, acts as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI)[2][3].

Name	1,1,2,2,3,3,4,4-octadeuteriobutane-1,4-diamine,dihydrochloride
Synonyms	butane-1,4-diamine dihydrochloride 1,4-Butanediamine, hydrochloride (1:2) 1,4-Diamino(butane-d8) dihydrochloride butane-1,4-diaminium dichloride 1,4-Butane-d8-diamine dihydrochloride 1,4-Butanediamine dihydrochloride Putrescine-d8 dihydrochloride

Description	1,4-Diaminobutane-d8 (dihydrochloride) is the deuterium labeled 1,4-Diaminobutane dihydrochloride[1]. 1,4-Diaminobutane (Putrescine) dihydrochloride is an endogenous metabolite, acts as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI)[2][3].
Related Catalog	Research Areas >> Endocrinology
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Hauschild MZ. Putrescine (1,4-diaminobutane) as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI). Ecotoxicol Environ Saf. 1993 Oct;26(2):228-47. [3]. E B Sequerra, et al. Putrescine as an important source of GABA in the postnatal rat subventricular zone. Neuroscience. 2007 May 11146(2):489-93.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
RIDADR	NONH for all modes of transport