butane-1,4-diaminium dichloride

Modify Date: 2024-01-09 18:10:22

butane-1,4-diaminium dichloride Structure
butane-1,4-diaminium dichloride structure
Common Name butane-1,4-diaminium dichloride
CAS Number 284665-22-1 Molecular Weight 161.073
Density N/A Boiling Point N/A
Molecular Formula C4H14Cl2N2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of butane-1,4-diaminium dichloride


1,4-Diaminobutane-d8 (dihydrochloride) is the deuterium labeled 1,4-Diaminobutane dihydrochloride[1]. 1,4-Diaminobutane (Putrescine) dihydrochloride is an endogenous metabolite, acts as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI)[2][3].

 Names

Name 1,1,2,2,3,3,4,4-octadeuteriobutane-1,4-diamine,dihydrochloride
Synonym More Synonyms

 butane-1,4-diaminium dichloride Biological Activity

Description 1,4-Diaminobutane-d8 (dihydrochloride) is the deuterium labeled 1,4-Diaminobutane dihydrochloride[1]. 1,4-Diaminobutane (Putrescine) dihydrochloride is an endogenous metabolite, acts as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI)[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Hauschild MZ. Putrescine (1,4-diaminobutane) as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI). Ecotoxicol Environ Saf. 1993 Oct;26(2):228-47.  

[3]. E B Sequerra, et al. Putrescine as an important source of GABA in the postnatal rat subventricular zone. Neuroscience. 2007 May 11146(2):489-93.  

 Chemical & Physical Properties

Molecular Formula C4H14Cl2N2
Molecular Weight 161.073
Exact Mass 160.053406
PSA 52.04000
LogP 2.68860

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
RIDADR NONH for all modes of transport

 Synonyms

butane-1,4-diamine dihydrochloride
1,4-Butanediamine, hydrochloride (1:2)
1,4-Diamino(butane-d8) dihydrochloride
butane-1,4-diaminium dichloride
1,4-Butane-d8-diamine dihydrochloride
1,4-Butanediamine dihydrochloride
Putrescine-d8 dihydrochloride