Name | 4,4'-(6-Chloropyrimidine-2,4-diyl)dimorpholine |
---|---|
Synonyms |
4,4'-(6-Chloro-2,4-pyrimidinediyl)dimorpholine
Morpholine, 4,4'-(6-chloro-2,4-pyrimidinediyl)bis- 4-(4-chloro-6-morpholin-4-ylpyrimidin-2-yl)morpholine |
Density | 1.3±0.1 g/cm3 |
---|---|
Boiling Point | 508.7±60.0 °C at 760 mmHg |
Melting Point | 139-142℃ |
Molecular Formula | C12H17ClN4O2 |
Molecular Weight | 284.742 |
Flash Point | 261.5±32.9 °C |
Exact Mass | 284.104004 |
PSA | 50.72000 |
LogP | 0.83 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Index of Refraction | 1.576 |
Storage condition | 2-8°C |
~92% 10244-24-3 |
Literature: NOVARTIS AG; CALIENNI, John Vincent; DE LA CRUZ, Marilyn; FLUBACHER, Dietmar; GONG, Baoqing; KAPA, Prasad Koteswara; KARPINSKI, Piotr H.; LIU, Hui; MICHEL, Pascal; MOSE, Rasmus; TESTA, Maria Caterina; WAYKOLE, Liladhar Murlidhar Patent: WO2012/44727 A2, 2012 ; Location in patent: Page/Page column 62-63 ; |
~98% 10244-24-3 |
Literature: Burger, Matthew T.; Pecchi, Sabina; Wagman, Allan; Ni, Zhi-Jie; Knapp, Mark; Hendrickson, Thomas; Atallah, Gordana; Pfister, Keith; Zhang, Yanchen; Bartulis, Sarah; Frazier, Kelly; Ng, Simon; Smith, Aaron; Verhagen, Joelle; Haznedar, Joshua; Huh, Kay; Iwanowicz, Ed; Xin, Xiaohua; Menezes, Daniel; Merritt, Hanne; Lee, Isabelle; Wiesmann, Marion; Kaufman, Susan; Crawford, Kenneth; Chin, Michael; Bussiere, Dirksen; Shoemaker, Kevin; Zaror, Isabel; Maira, Sauveur-Michel; Voliva, Charles F. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 774 - 779 |
~57% 10244-24-3
Detail
|
Literature: WO2008/98058 A1, ; Page/Page column 57-58 ; WO 2008/098058 A1 |
~78% 10244-24-3 |
Literature: ACS Medicinal Chemistry Letters, , vol. 2, # 10 p. 774 - 779 |
~% 10244-24-3 |
Literature: WO2007/84786 A1, ; Page/Page column 123 ; WO 2007/084786 A1 |
Precursor 3 | |
---|---|
DownStream 1 | |
HS Code | 2934999090 |
---|---|
Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |