19031-55-1

19031-55-1 structure

Name: (2,2,5,5-2H4)Hexanedioic acid
Chemical Name: 2,2,5,5-tetradeuteriohexanedioic acid
CAS Number: 19031-55-1
Molecular Formula: C₆H₆D₄O₄
Molecular Weight: 150.166
Catalog: Research Areas Metabolic Disease
Create Date: 2018-04-15 08:00:00
Modify Date: 2024-01-11 12:55:52
Adipic acid-d4-1 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

Name	2,2,5,5-tetradeuteriohexanedioic acid
Synonyms	Hexanedioic-2,2,5,5-d4 acid Adipic acid-2,2,5,5-d4 2,2,5,5-tetradeuterio-hexanedioic acid (2,2,5,5-H)Hexanedioic acid 2,2,5,5-Tetradeuteroadipinsaeure Hexanedioic-2,2,5,5-d acid

Description	Adipic acid-d4-1 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. G.Frauendienst-Egger, Friedrich K. Trefz (2017). MetaGene: Metabolic & Genetic Information Center. METAGENE consortium.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36
Safety Phrases	26
RIDADR	UN 3077 9 / PGIII

124-04-9

19031-55-1

136665-53-7

19031-55-1

Precursor 2
124-04-9 136665-53-7
DownStream 0