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63449-41-2

63449-41-2 structure
63449-41-2 structure

Name Benzalkonium chloride
Synonyms N-Benzyl-N,N-dimethyl-1-decanaminium chloride
Benzenemethanaminium, N-decyl-N,N-dimethyl-, chloride
Benzyl-C8-18-alkyldimethylammonium chlorides
MFCD00145757
Benzenemethanaminium, N-decyl-N,N-dimethyl-, chloride (1:1)
EINECS 264-151-6
N-benzyl-N,N-dimethyldecan-1-aminium chloride
Description Benzalkonium chloride (50% in Water) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
Density 0.989 g/cm3
Boiling Point 100ºC
Melting Point -5ºC
Molecular Formula C22H40ClN
Molecular Weight 311.933
Flash Point >100ºC
Exact Mass 311.237976
LogP 7.37600
Water Solubility Miscible with water, methanol and acetone.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BO3151000
CHEMICAL NAME :
Ammonium, alkyl(C14-16)dimethylbenzyl-, chlorides
CAS REGISTRY NUMBER :
63449-41-2
LAST UPDATED :
199710

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1420 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Blood - hemorrhage
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 12,1593,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Blood - hemorrhage
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 12,1593,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
16 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 38,428,1949 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
650 mg/kg/13W-I
TOXIC EFFECTS :
Liver - liver function tests impaired Kidney, Ureter, Bladder - urine volume increased Blood - changes in bone marrow (not otherwise specified)
REFERENCE :
KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 12(12),61,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
850 mg/kg/30D-I
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 38,428,1949
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
9100 mg/kg/52W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - chronic pulmonary edema Gastrointestinal - other changes Related to Chronic Data - death
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,584,1961 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
Symbol GHS05 GHS09
GHS05, GHS09
Signal Word Danger
Hazard Statements H314-H400
Precautionary Statements P273-P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C: Corrosive;N: Dangerous for the environment;
Risk Phrases R21/22;R34;R50
Safety Phrases 36/37/39-45-61
RIDADR UN 2923
WGK Germany 3
RTECS BO3151000
Packaging Group III
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