94987-08-3

94987-08-3 structure

Name: Gypenoside XLIX
Chemical Name: (3β)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy}-20-hydroxy-19-oxodammar-24-en-21-yl β-D-glucopyranoside
CAS Number: 94987-08-3
Molecular Formula: C₅₂H₈₆O₂₁
Molecular Weight: 1047.227
Catalog: Biochemical Plant extracts
Create Date: 2018-03-22 08:00:00
Modify Date: 2024-01-04 11:30:31
Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G. pentaphyllum. Gypenoside XLIX is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator and inhibits cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) overexpression and hyperactivity in human endothelial cells[1].

Name	(3β)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy}-20-hydroxy-19-oxodammar-24-en-21-yl β-D-glucopyranoside
Synonyms	(3β)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy}-20-hydroxy-19-oxodammar-24-en-21-yl β-D-glucopyranoside Dammar-24-en-19-al, 3-[[O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy]-21-(β-D-glucopyranosyloxy)-20-hydroxy-, (3β)- Gypenoside XLIX

Description	Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G. pentaphyllum. Gypenoside XLIX is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator and inhibits cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) overexpression and hyperactivity in human endothelial cells[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Inflammation/Immunology
Target	PPAR-α
References	[1]. Huang TH , et al. Gypenoside XLIX, a naturally occurring PPAR-alpha activator, inhibits cytokine-induced vascular cell adhesion molecule-1 expression and activity in human endothelial cells. Eur J Pharmacol. 2007 Jun 22;565(1-3):158-65.