Gypenoside XLIX

Modify Date: 2024-01-04 11:30:31

Gypenoside XLIX Structure
Gypenoside XLIX structure
Common Name Gypenoside XLIX
CAS Number 94987-08-3 Molecular Weight 1047.227
Density 1.4±0.1 g/cm3 Boiling Point 1105.1±65.0 °C at 760 mmHg
Molecular Formula C52H86O21 Melting Point N/A
MSDS N/A Flash Point 306.9±27.8 °C

 Use of Gypenoside XLIX


Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G. pentaphyllum. Gypenoside XLIX is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator and inhibits cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) overexpression and hyperactivity in human endothelial cells[1].

 Names

Name (3β)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy}-20-hydroxy-19-oxodammar-24-en-21-yl β-D-glucopyranoside
Synonym More Synonyms

 Gypenoside XLIX Biological Activity

Description Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G. pentaphyllum. Gypenoside XLIX is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator and inhibits cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) overexpression and hyperactivity in human endothelial cells[1].
Related Catalog
Target

PPAR-α

References

[1]. Huang TH , et al. Gypenoside XLIX, a naturally occurring PPAR-alpha activator, inhibits cytokine-induced vascular cell adhesion molecule-1 expression and activity in human endothelial cells. Eur J Pharmacol. 2007 Jun 22;565(1-3):158-65.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1105.1±65.0 °C at 760 mmHg
Molecular Formula C52H86O21
Molecular Weight 1047.227
Flash Point 306.9±27.8 °C
Exact Mass 1046.566162
PSA 333.67000
LogP 5.46
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.615
Storage condition 2-8C

 Synonyms

(3β)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy}-20-hydroxy-19-oxodammar-24-en-21-yl β-D-glucopyranoside
Dammar-24-en-19-al, 3-[[O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->3)]-α-L-arabinopyranosyl]oxy]-21-(β-D-glucopyranosyloxy)-20-hydroxy-, (3β)-
Gypenoside XLIX
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