14144-06-0

14144-06-0 structure

Name: Diosgenin glucoside
Chemical Name: Trillin
CAS Number: 14144-06-0
Molecular Formula: C₃₃H₅₂O₈
Molecular Weight: 576.761
Catalog: Biochemical Natural product
Create Date: 2018-08-29 19:01:36
Modify Date: 2026-07-01 20:28:30
Diosgenin glucoside, a saponin compound extracted from Tritulus terrestris L., provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis [1][2].

Name	Trillin
Synonyms	Tibllin LilioglycosideA β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl diosgenin 3-O-beta-D-glucoside [(25R)-Spirost-5-en-3β-yl]β-D-glucopyranoside Polyphyllin A Diosgenin 3-glucoside TRILLIN (25R)-3β-(β-D-Glucopyranosyloxy)spirost-5-ene Disogluside, AlliuMoside A Polygonatoside A diosgeninglucoside (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(((4S,5'R,6,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-yl)oxy)tetrahydro-2H-py Collettiside I Trillin(Diosgenin glucoside) TRILLIN (RG) (25R)-3b-(beta-D-Glucopyranosyloxy)spirost-5-ene Trillin from Trillium tschonoskii Maxim Diosgenin 3-b-D-glucoside (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(((2'R,4S,5'R,6,6bS,8aS,8bR,9S,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol Diosgenin 3-O-b-D-glucopyranoside PolyphyllinA Trillin-RM Diosgenin b-D-glucoside Funkioside A Collettinside I Melongoside B iosgenin glucoside (25R)-3b-(b-D-Glucopyranosyloxy)spirost-5-ene Disogluside Prosapogenin D'3 Lilioglycoside A Diosgenin glucoside //BP Alliumoside A (3β,25R)-Spirost-5-en-3-yl β-D-glucopyranoside

Description	Diosgenin glucoside, a saponin compound extracted from Tritulus terrestris L., provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis [1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Int Immunopharmacol. 2017 Sep;50:22-29. doi: 10.1016/j.intimp.2017.06.008. Epub 2017 Jun 14. [2]. Chen XB, et al. Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis. Int J Mol Sci. 2018 Aug 2;19(8). pii: E2274.