- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone
- Price: ￥548.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: nomilin
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
1063-77-0
1063-77-0 structure
- Name: 1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone
- Chemical Name: Nomilin
- CAS Number: 1063-77-0
- Molecular Formula: C28H34O9
- Molecular Weight: 514.564
- Catalog: Biochemical Natural product
- Create Date: 2018-09-16 22:39:30
- Modify Date: 2024-01-02 13:36:00
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Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2].
| Name | Nomilin |
|---|---|
| Synonyms |
fromcitrusseeds
1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone Oxireno[4',5']pyrano[4',3':5,6]naphth[2,1-c]oxepin-3,10,12(1H,4H,10aH)-trione, 5-(acetyloxy)-8-(3-furanyl)decahydro-1,1,5a,7a,11b-pentamethyl-, (5S,5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)- (5S,5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-3,10,12-trioxohexadecahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepin-5-yl acetate (5S,5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)-8-(3-Furyl)-1,1,5a,7a,11b-pentamethyl-3,10,12-trioxohexadecahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepin-5-yl acetate 1-(3-Furyl)decahydro-11-hydroxy-4b,7,7,11a,13a-pentamethyloxireno(4,4a)-2-benzopyrano[6,5-g](2)benzoxepin-3,5,9(3aH,4bH,6H)-trione Acetate |
| Description | Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Nomilin treatment significantly mitigated cell death and decreased lactate dehydrogenase (LDH) release and ROS production in SH-SY5Y cells induced by oxygen-glucose deprivation (OGD), which was almost abolished by Nrf2 knockdown[1]. |
| In Vivo | Nomilin attenuated blood-brain barrier (BBB) disruption in MCAO rats, which might be associated with alleviating the loss of tight junction proteins, including ZO-1 and occludin-5[1]. |
| References |
[2]. Sato R, et al. Nomilin as an anti-obesity and anti-hyperglycemic agent. Vitam Horm. 2013;91:425-39. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 657.7±55.0 °C at 760 mmHg |
| Melting Point | 278-279° |
| Molecular Formula | C28H34O9 |
| Molecular Weight | 514.564 |
| Flash Point | 351.6±31.5 °C |
| Exact Mass | 514.220276 |
| PSA | 121.64000 |
| LogP | 2.47 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.575 |