1063-77-0
1063-77-0 structure
- Name: 1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone
- Chemical Name: Nomilin
- CAS Number: 1063-77-0
- Molecular Formula: C28H34O9
- Molecular Weight: 514.564
- Catalog: Biochemical Natural product
- Create Date: 2018-09-16 22:39:30
- Modify Date: 2026-07-01 12:53:08
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Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2].
| Name | Nomilin |
|---|---|
| Synonyms |
NoMilin, froM Rutaceae
NOMILIN fromcitrusseeds Nomilin //BP Nomilin from Rutaceae (5S,5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-3,10,12-trioxohexadecahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepin-5-yl acetate normilin NOMILIN(RG) tianfu chem Nomilin (1S,3aS,4,4bR,6,11S,11,11bR,13aS)-1-(Furan-3-yl)-4b,7,7,11a,13a-pentamethyl-3,5,9-trioxohexadecahydrooxino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromen-11-yl acetate 1-(Acetyloxy)-1,2-dihydroobacunoic acid ε-lactone Oxireno[4,4a]-2-benzopyrano[6,5-g]benzoxin-3,5,9(3aH,4bH,6H)-trione, 11-(acetyloxy)-1-(3-furanyl)decahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4,4bR,6,11S,11,11bR,13aS) CCRIS NOMILIN(P) Nomilin(SH) (5S,5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)-8-(3-Furyl)-1,1,5a,7a,11b-pentamethyl-3,10,12-trioxohexadecahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepin-5-yl acetate 1-(3-Furyl)decahydro-11-hydroxy-4b,7,7,11a,13a-pentamethyloxireno(4,4a)-2-benzopyrano[6,5-g](2)benzoxepin-3,5,9(3aH,4bH,6H)-trione Acetate Nomilin (~) (1S,3aS,4,4bR,6,11S,11,11bR,13aS)-11-(Acetyloxy)-1-(3-furanyl)decahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g]benzoxin-3,5,9(3aH,4bH,6H)-trione 1-(Acetyloxy)-1,2-dihydroobacunoic acid islon-lactone NOMILIN(P)(CALL) |
| Description | Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Nomilin treatment significantly mitigated cell death and decreased lactate dehydrogenase (LDH) release and ROS production in SH-SY5Y cells induced by oxygen-glucose deprivation (OGD), which was almost abolished by Nrf2 knockdown[1]. |
| In Vivo | Nomilin attenuated blood-brain barrier (BBB) disruption in MCAO rats, which might be associated with alleviating the loss of tight junction proteins, including ZO-1 and occludin-5[1]. |
| References |
[2]. Sato R, et al. Nomilin as an anti-obesity and anti-hyperglycemic agent. Vitam Horm. 2013;91:425-39. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 657.7±55.0 °C at 760 mmHg |
| Melting Point | 278-279° |
| Molecular Formula | C28H34O9 |
| Molecular Weight | 514.564 |
| Flash Point | 351.6±31.5 °C |
| Exact Mass | 514.220276 |
| PSA | 121.64000 |
| LogP | 2.47 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.575 |