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919-30-2

919-30-2 structure
919-30-2 structure
  • Name: 3-Aminopropyltriethoxysilane
  • Chemical Name: (3-Aminopropyl)triethoxysilane
  • CAS Number: 919-30-2
  • Molecular Formula: C9H23NO3Si
  • Molecular Weight: 221.369
  • Catalog: Chemical reagent Organic reagent Boric acid
  • Create Date: 2018-03-07 08:00:00
  • Modify Date: 2024-01-02 15:41:21
  • 3-Aminopropyltriethoxysilane is a common method for biomolecule immobilization on silicon and silicon derivatives such as silicon nitride (Si3N4)[1].

Name (3-Aminopropyl)triethoxysilane
Synonyms 3-(triethoxysilyl)propan-1-amine
MFCD00025614
1-Propanamine, 3-(triethoxysilyl)-
(3-Aminopropyl)triethoxysilane
(γ-Aminopropyl)triethoxysilane
3-aminopropyl-triethoxysilane
3-aminopropyltriethoxy silane
APTES
1-Propanamine, 3- (triethoxysilyl)-
3-aminopropyl triethoxysilane
3-(Triethoxysilyl)-1-propanamine
Propylamine, 3- (triethoxysilyl)-
γ-aminopropyltriethoxysilane
γ-Aminopropyltriethoxy silane
3-Aminopropyltriethoxysilane
EINECS 213-048-4
Silane, (γ-aminopropyl)triethoxy-
3-aminopropyl(triethoxy)silane
Aminopropyltriethoxysilane
KH-550
Description 3-Aminopropyltriethoxysilane is a common method for biomolecule immobilization on silicon and silicon derivatives such as silicon nitride (Si3N4)[1].
Related Catalog
References

[1]. Saengdee P, et al. Optimization of 3-aminopropyltriethoxysilane functionalization on silicon nitride surface for biomolecule immobilization. Talanta. 2020;207:120305.

Density 0.9±0.1 g/cm3
Boiling Point 222.1±13.0 °C at 760 mmHg
Melting Point -70 °C
Molecular Formula C9H23NO3Si
Molecular Weight 221.369
Flash Point 104.4±0.0 °C
Exact Mass 221.144714
PSA 53.71000
LogP 1.37
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.433
Storage condition Store at RT.
Stability Stable. Incompatible with acids, strong oxidizing agents. May decompose on exposure to moisture.
Water Solubility REACTS

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX2100000
CHEMICAL NAME :
1-Propanamine, 3-(triethoxysilyl)-
CAS REGISTRY NUMBER :
919-30-2
BEILSTEIN REFERENCE NO. :
1754988
LAST UPDATED :
199710
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C9-H23-N-O3-Si
MOLECULAR WEIGHT :
221.42
WISWESSER LINE NOTATION :
Z3-SI-O2&O2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1233,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/19/1972
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1233,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Behavioral - excitement Lungs, Thorax, or Respiration - emphysema Blood - changes in leukocyte (WBC) count
REFERENCE :
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 11,118,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RCRVAB Russian Chemical Reviws (English Translation). Translation of USKHAB. (Royal Soc. of Chemistry, Distribution Centre, Blackhorse Rd., Letchworth, Herts SG6 1HN, UK) V.29- 1960- Volume(issue)/page/year: 38,975,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
4 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/19/1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHABA8 Chemical Abstracts. (Chemical Abstracts Service, Box 3012, Columbus, OH 43210) V.1- 1907- Volume(issue)/page/year: 70,36149,1969 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
147 mg/m3/6H/4W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Nutritional and Gross Metabolic - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0526411-2 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1992 No. of Facilities: 210 (estimated) No. of Industries: 6 No. of Occupations: 5 No. of Employees: 874 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1992 No. of Facilities: 1723 (estimated) No. of Industries: 22 No. of Occupations: 34 No. of Employees: 33590 (estimated) No. of Female Employees: 5422 (estimated)
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H314-H317
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive
Risk Phrases R22;R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2735 8/PG 2
WGK Germany 1
RTECS TX2100000
Packaging Group III
Hazard Class 8
HS Code 29310095

~80%

919-30-2 structure

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Literature: Dynamit Nobel Aktiengesellschaft Patent: US4234503 A1, 1980 ;

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Literature: Toa Nenryo Kogyo Kabushiki Kaisha Patent: US4897501 A1, 1990 ;

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Detail
Literature: Tonen Corporation Patent: EP284447 B1, 1991 ;

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Literature: Toshiba Silicone Co., Ltd. Patent: US4649208 A1, 1987 ;

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Literature: Chemical Communications, , # 1 p. 116 - 118

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Literature: Journal of Organic Chemistry, , vol. 24, p. 119

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Literature: Mem.Fac.Eng.Osaka City Univ., , vol. 1, p. 1,6,11

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Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 53, # 7 p. 1591 - 1596,1435 - 1439

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Literature: Chernyshev; Belyakova; Knyazeva; Pomerantseva; Efimova Russian Chemical Bulletin, 1998 , vol. 47, # 7 p. 1374 - 1378
HS Code 29310095