Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Diethyl chlorothiophosphate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

2524-04-1

2524-04-1 structure

Name: Diethyl chlorothiophosphate
Chemical Name: Diethyl chlorothiophosphate
CAS Number: 2524-04-1
Molecular Formula: C₄H₁₀ClO₂PS
Molecular Weight: 188.61300
Catalog: Biochemical Nucleoside drugs Nucleotides and their analogues
Create Date: 2018-06-30 23:06:23
Modify Date: 2024-01-02 18:41:00

Name	Diethyl chlorothiophosphate
Synonyms	DECTP Ethyl PCT,refined O,O-diethyl chlorothiophosphate U.N. 2751 Diethylchlorthiofosfat diethyl thiophosphoryl chloride EINECS 219-755-4 ETHYL INTERMEDIARY EP-1 O,O-diethyl phosphorochloridothioate O,O-diethyl phosphorochloridothionate diethylphosphorochloridothioate O,O-diethyl chlorothionophosphate Diethyl chlrothiophosphate MFCD00009088 ETHYL PCT DEPCT

Density	1.2 g/mL at 25 °C(lit.)
Boiling Point	96 °C
Melting Point	-75℃
Molecular Formula	C₄H₁₀ClO₂PS
Molecular Weight	188.61300
Flash Point	>230 °F
Exact Mass	187.98300
PSA	60.36000
LogP	3.17330
Vapour Pressure	0.152mmHg at 25°C
Index of Refraction	n20/D 1.472(lit.)
Water Solubility	hydrolyzes, immiscible

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TD1780000

CHEMICAL NAME :: Phosphorochloridothioic acid, O,O-diethyl ester

CAS REGISTRY NUMBER :: 2524-04-1

BEILSTEIN REFERENCE NO. :: 0471434

LAST UPDATED :: 199710

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C4-H10-Cl-O2-P-S

MOLECULAR WEIGHT :: 188.62

WISWESSER LINE NOTATION :: 2OPS&GO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1340 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Blood - hemorrhage

REFERENCE :: HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(10-12),334,1968

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1172,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,51,1982

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 725 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,51,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 56(5),6,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Blood - hemorrhage

REFERENCE :: HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(10-12),334,1968

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,393,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 810 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Blood - hemorrhage

REFERENCE :: HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(10-12),334,1968 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 mg/m3/24H/17W-C

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 56(5),6,1991 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4068 No. of Facilities: 30 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 1088 (estimated) No. of Female Employees: 187 (estimated)

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H301-H311-H314-H331
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T+:Verytoxic;
Risk Phrases	R21/22;R26;R34
Safety Phrases	S23-S26-S36/37/39-S45-S28A
RIDADR	UN 2751 8/PG 2
WGK Germany	3
RTECS	TD1780000
Packaging Group	II
Hazard Class	8
HS Code	2920190090

Precursor 9
298-06-6 141-52-6 64-17-5 999-01-9
594-71-8 71774-85-1 3268-79-9 814-49-3
928-57-4
DownStream 5
56-72-4 333-41-5 3689-24-5 22439-40-3
93516-19-9

HS Code	2931900090
Summary	2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

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