58186-27-9
58186-27-9 structure
- Name: Idebenone
- Chemical Name: idebenone
- CAS Number: 58186-27-9
- Molecular Formula: C19H30O5
- Molecular Weight: 338.439
- Catalog: API Nervous system medication Brain metabolism regulating drug
- Create Date: 2018-05-21 08:00:00
- Modify Date: 2026-07-13 19:50:53
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Idebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects.Target: OthersIdebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects. Idebenone was generally well tolerated with similar numbers of adverse events in each group. One child receiving high-dose idebenone developed neutropenia after 6 months, which resolved after discontinuation of treatment. 8OH2′dG concentrations were not increased, and did not significantly change with idebenone treatment [1]. The 2-year efficacy and safety of idebenone were studied in a prospective, randomized, double-blind multicentre study in 3 parallel groups of patients with dementia of the Alzheimer type (DAT) of mild to moderate degree. A total of 450 patients were randomized to either placebo for 12 months, followed by idebenone 90 mg tid for another 12 months (n = 153) or idebenone 90 mg tid for 24 months (n = 148) or 120 mg tid for 24 months (n = 149). idebenone showed statistically significant dose-dependent improvement in the primary efficacy variable ADAS-Total and in all the secondary efficacy variables [2].
| Name | idebenone |
|---|---|
| Synonyms |
API Nootropics Powder Idebenone CAS58-9for Brain Improvement
6-(10-Hydroxydecyl)ubiquinone Catena Idebenone - Bio-X 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone 2-(10-Hydroxydecyl)-5，6-dimethoxy-3-methyl-2，5-cyclohexadienPl，4-dione Idebenone-d6 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione Idebenone Idebenone Ai benzoquinone 2-(10-HYDROXY-DECYL)-5,6-DIMETHOXY-3-METHYL-[1,4]BENZOQUINONE 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-5-cyclohexadiene-1,4-dione 2,3-Dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone Idebenone powder Nanoactive Idebenone IdebenoneMin Idebenone> 2,5-Cyclohexadiene-1,4-dione, 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl Lucenabol Idevenone Idebenona [Spanish] 2,5-Cyclohexadiene-1,4-dione, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl Idebenone [INN:JAN] Daruma Duma QSA-10 CV 2619 Idebenzone 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione IDEBENONE(P) Nano Liposomal Idebenone Idibenzoquinone Cerestabon 5,6-Dimethoxy-2-(10-hydroxydecyl)-3-methyl-1,4-benzoquinone 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone Idebenone (JAN) Mnesis 6-(10 Raxone Idebenone (CV-2619) Idebenone, 10 mM in DMSO Sovrima 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylbenzo-1,4-quinone idebonone aibendikun IDEBENONE(PATENTED-NOSUPPLY) UNII-HB6PN45W4J Idebenone, antioxidant and neuroprotective agent Idebenone //BP Avan Idebenone API Duma：Mnesis IdebenoneQ: What is Idebenone Q: What is the CAS Number of Idebenone Q: What is the storage condition of Idebenone Q: What e the applications of Idebenone Idebenonum [Latin] 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-cyclohexa-2,5-diene-1,4-dione MFCD00274552 4-dione,5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-5-cyclohexadiene-1 Idebenon 2,5-Cyclohexadiene-1,4-dione, 2-(10-hydroxydecyl)-5,6-dimethoxy-3 debenone IDEBENONE 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione cv 2619 idebenone Idebenone NanoLiposome Idebenone 58-9 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone |
| Description | Idebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects.Target: OthersIdebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects. Idebenone was generally well tolerated with similar numbers of adverse events in each group. One child receiving high-dose idebenone developed neutropenia after 6 months, which resolved after discontinuation of treatment. 8OH2′dG concentrations were not increased, and did not significantly change with idebenone treatment [1]. The 2-year efficacy and safety of idebenone were studied in a prospective, randomized, double-blind multicentre study in 3 parallel groups of patients with dementia of the Alzheimer type (DAT) of mild to moderate degree. A total of 450 patients were randomized to either placebo for 12 months, followed by idebenone 90 mg tid for another 12 months (n = 153) or idebenone 90 mg tid for 24 months (n = 148) or 120 mg tid for 24 months (n = 149). idebenone showed statistically significant dose-dependent improvement in the primary efficacy variable ADAS-Total and in all the secondary efficacy variables [2]. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 497.3±45.0 °C at 760 mmHg |
| Melting Point | 52-550C |
| Molecular Formula | C19H30O5 |
| Molecular Weight | 338.439 |
| Flash Point | 170.1±22.2 °C |
| Exact Mass | 338.209320 |
| PSA | 72.83000 |
| LogP | 3.49 |
| Vapour Pressure | 0.0±2.9 mmHg at 25°C |
| Index of Refraction | 1.502 |
| Storage condition | Room temp |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Hazard Codes | Xi: Irritant; |
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| RIDADR | NONH for all modes of transport |
| RTECS | GU5290000 |
| Precursor 8 | |
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| DownStream 2 | |
