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55954-61-5

55954-61-5 structure
55954-61-5 structure
  • Name: Pseudohypericin
  • Chemical Name: pseudohypericin
  • CAS Number: 55954-61-5
  • Molecular Formula: C30H16O9
  • Molecular Weight: 520.443
  • Catalog: Signaling Pathways Anti-infection HIV
  • Create Date: 2018-05-21 08:00:00
  • Modify Date: 2024-01-05 18:24:22
  • Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity[1][2].

Name pseudohypericin
Synonyms Phenanthro(1,10,9,8-opgra)perylene-7,14-dione,1,3,4,6,8,13-hexahydroxy-10-(hydroxymethyl)-11-methyl-,stereoisomer
1,3,4,6,8,13-hexahydroxy-10-hydroxymethyl-11-methyl-phenanthro[1,10,9,8-opqra]perylene-7,14-dione
Psuedohypericin
1,3,4,6,8,13-Hexahydroxy-10-hydroxymethyl-11-methyl-phenanthro[1,10,9,8-opqra]perylen-7,14-dion
C30H16O9
1,3,4,6,8,13-Hexahydroxy-10-(hydroxymethyl)-11-methylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
Phenanthro[1,10,9,8-opqra]perylene-7,14-dione, 1,3,4,6,8,13-hexahydroxy-10-(hydroxymethyl)-11-methyl-
BIDD:PXR0086
MFCD00133794
Description Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity[1][2].
Related Catalog
In Vitro Pseudohypericin shows antiretroviral activity[1].
References

[1]. Lavie G, et al. Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin. Proc Natl Acad Sci U S A. 1989 Aug;86(15):5963-7.

[2]. Zheng X, et al. Apoptosis of THP-1 Macrophages Induced by Pseudohypericin-Mediated Sonodynamic Therapy Through the Mitochondria-Caspase Pathway. Cell Physiol Biochem. 2016;38(2):545-57.

Density 2.0±0.1 g/cm3
Boiling Point 994.7±65.0 °C at 760 mmHg
Molecular Formula C30H16O9
Molecular Weight 520.443
Flash Point 569.2±30.8 °C
Exact Mass 520.079407
PSA 175.75000
LogP 6.75
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 2.169
Storage condition 2-8°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Hazard Codes Xi
Risk Phrases 22
Safety Phrases 22-36
RIDADR NONH for all modes of transport