Pseudohypericin

Modify Date: 2024-01-05 18:24:22

Pseudohypericin Structure
Pseudohypericin structure
Common Name Pseudohypericin
CAS Number 55954-61-5 Molecular Weight 520.443
Density 2.0±0.1 g/cm3 Boiling Point 994.7±65.0 °C at 760 mmHg
Molecular Formula C30H16O9 Melting Point N/A
MSDS Chinese USA Flash Point 569.2±30.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Pseudohypericin


Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity[1][2].

 Names

Name pseudohypericin
Synonym More Synonyms

 Pseudohypericin Biological Activity

Description Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity[1][2].
Related Catalog
In Vitro Pseudohypericin shows antiretroviral activity[1].
References

[1]. Lavie G, et al. Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin. Proc Natl Acad Sci U S A. 1989 Aug;86(15):5963-7.

[2]. Zheng X, et al. Apoptosis of THP-1 Macrophages Induced by Pseudohypericin-Mediated Sonodynamic Therapy Through the Mitochondria-Caspase Pathway. Cell Physiol Biochem. 2016;38(2):545-57.

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 994.7±65.0 °C at 760 mmHg
Molecular Formula C30H16O9
Molecular Weight 520.443
Flash Point 569.2±30.8 °C
Exact Mass 520.079407
PSA 175.75000
LogP 6.75
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 2.169
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Hazard Codes Xi
Risk Phrases 22
Safety Phrases 22-36
RIDADR NONH for all modes of transport

 Articles26

More Articles
Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions.

Phytother Res. 28(5) , 643-55, (2014)

Hypericum perforatum (HP) belongs to the Hypericaceae family and is one of the oldest used and most extensively investigated medicinal herbs. The medicinal form comprises the leaves and flowering tops...

The main components of St John's Wort inhibit low-density lipoprotein atherogenic modification: a beneficial "side effect" of an OTC antidepressant drug?

Free Radic. Res. 41(2) , 234-41, (2007)

Hypericin and pseudohypericin are polycyclic-phenolic structurally related compounds found in Hypericum perforatum L. (St John's wort). As hypericin has been found to bind to LDL one may assume that i...

Rapid and efficient purification of naphthodianthrones from St. John's wort extract by using liquid-liquid extraction and SEC.

J. Sep. Sci. 32(9) , 1374-82, (2009)

Hypericin and pseudohypericin, the main naphthodianthrones present in Hypericum species are among the most promising natural products, but the research concerning their biological activities is hinder...

 Synonyms

Phenanthro(1,10,9,8-opgra)perylene-7,14-dione,1,3,4,6,8,13-hexahydroxy-10-(hydroxymethyl)-11-methyl-,stereoisomer
1,3,4,6,8,13-hexahydroxy-10-hydroxymethyl-11-methyl-phenanthro[1,10,9,8-opqra]perylene-7,14-dione
Psuedohypericin
1,3,4,6,8,13-Hexahydroxy-10-hydroxymethyl-11-methyl-phenanthro[1,10,9,8-opqra]perylen-7,14-dion
C30H16O9
1,3,4,6,8,13-Hexahydroxy-10-(hydroxymethyl)-11-methylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
Phenanthro[1,10,9,8-opqra]perylene-7,14-dione, 1,3,4,6,8,13-hexahydroxy-10-(hydroxymethyl)-11-methyl-
BIDD:PXR0086
MFCD00133794
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