104224-63-7
104224-63-7 structure
- Name: 2-(1-Adamantyl)-4-bromo anisole
- Chemical Name: 2-(1-Adamantyl)-4-bromoanisole
- CAS Number: 104224-63-7
- Molecular Formula: C17H21BrO
- Molecular Weight: 321.252
- Catalog: Pharmaceutical intermediate API intermediate
- Create Date: 2018-12-19 16:27:35
- Modify Date: 2026-06-30 22:14:25
| Name | 2-(1-Adamantyl)-4-bromoanisole |
|---|---|
| Synonyms |
L66 B6/B-H/DI A B- C 1B ITJ BR CE FO1
1-(5-bromo-2-methoxyphenyl)-tricyclo[3,3,1,13,7]decane (intermediate of adapalene) Adap-int A (3s,5s,7s)-1-(5-Bromo-2-methoxyphenyl)adamantane 2-(1-Adamantyl)-4-bromo-anisole (Adapalene) TRICYCLO[3.3.1.13,7]DECANE, 1-(5-BROMO-2-METHOXYPHENYL) 1-(5-Brom-2-methoxyphenyl)tricyclo[3.3.1.1]decan 2-(1-ADAMANTYL)-4-BROMOANISOLE 2-(1-adamantanyl)-4-bromoanisole 2-(1-adamantyl)-4-bromophenetole 1-(5-Bromo-2-methoxy-phenyl)adamantane Anisole, 2-(1-adamantyl)-4-bromo 4-bromo-2-(tricyclo[3.3.1.1]dec-1-yl)phenyl methyl ether 1-(5-bromo-2-methoxyphenyl) 2-(1-ADAMANTANE)-4-BROMOANISOLE 2-Adamantyl-4-bromoanisole Adapalene IMpurity J 1-(5-Bromo-2-methoxyphenyl)tricyclo[3.3.1.1(3,7)]decane MFCD03855308 2-(Adamantan-1-yl)-4-bromoanisole, 2-(Adamantan-1-yl)-4-bromo-1-methoxybenzene (1 - ADMANTYL) - 4 BROMO ANISOLE 1-(5-Bromo-2-methoxy 1-(5-bromo-2-methoxy-phenyl)adamantane 1-(5-Bromo-2-methoxy-phenyl)adamantane ISO 9001：2015 REACH 2-Adamantyl-4-bromo-1-methoxybenzene 2-(Adamantan-1-yl)-4-bromoanisole, 2-(Adama 2-(1-Adamantyl)-4-bromoanisole > 1-(5-Bromo-2-methoxyphenyl)adamantane 2-(Adamantan-1-yl)-4-bromophenyl methyl ether 1-(5-BROMO-2-METHOXYPHENYL)TRYCYCLO[3,3,1,13,7]DECANE 1-(5-Bromo-2-methoxyphenyl)-tricyclo[3.3.1.13,7]decane |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 402.5±38.0 °C at 760 mmHg |
| Melting Point | 139-141°C |
| Molecular Formula | C17H21BrO |
| Molecular Weight | 321.252 |
| Flash Point | 160.3±12.8 °C |
| Exact Mass | 320.077576 |
| PSA | 9.23000 |
| LogP | 6.51 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.594 |
| Storage condition | Refrigerator |
| Hazard Codes | Xi: Irritant; |
|---|---|
| HS Code | 2909309090 |
|
~92%
104224-63-7 |
| Literature: AKAAL PHARMA PTY LTD; GILL, Gurmit S; GROBELNY, Damian W Patent: WO2010/43000 A1, 2010 ; Location in patent: Page/Page column 80 ; WO 2010/043000 A1 |
|
~82%
104224-63-7 |
| Literature: Wang, Nan; Wang, Ronghua; Shi, Xia; Zou, Gang Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 227 - 233 |
|
~92%
104224-63-7 |
| Literature: Liu, Zhichang; Xiang, Jiannan Organic Process Research and Development, 2006 , vol. 10, # 2 p. 285 - 288 |
|
~%
104224-63-7 |
| Literature: Journal of Medicinal Chemistry, , vol. 38, # 26 p. 4993 - 5006 |
|
~%
104224-63-7 |
| Literature: Journal of Medicinal Chemistry, , vol. 38, # 26 p. 4993 - 5006 |
| Precursor 6 | |
|---|---|
| DownStream 5 | |
![[3-(Adamantan-1-yl)-4-methoxyphenyl]boronic acid structure](https://image.chemsrc.com/caspic/368/459423-32-6.png)
![Mehtyl 6-[3-(1-adamanty)-4-methoxy phenyl]-2-naphthoate structure](https://image.chemsrc.com/caspic/057/106685-41-0.png)
| HS Code | 2909309090 |
|---|---|
| Summary | 2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |