130263-10-4

130263-10-4 structure

Name: Demethoxypiplartine
Chemical Name: 1-[3-(3,4-dimethoxyphenyl)prop-2-enoyl]piperidin-2-one
CAS Number: 130263-10-4
Molecular Formula: C₁₆H₁₇NO₄
Molecular Weight: 287.31
Catalog: Natural product Alkaloid
Create Date: 2017-08-29 14:08:58
Modify Date: 2024-01-11 19:09:45
Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC50 of 18.1 μg/mL[1].

Name	1-[3-(3,4-dimethoxyphenyl)prop-2-enoyl]piperidin-2-one
Synonyms	2(1H)-Pyridinone, 1-[(2E)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]-5,6-dihydro- Demethoxypiplartine 1-[(2E)-3-(3,4-Dimethoxyphenyl)-2-propenoyl]-5,6-dihydro-2(1H)-pyridinone

Description	Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC50 of 18.1 μg/mL[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Shi YN, et al. Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum. Planta Med. 2017 Jan;83(1-02):143-150.

Hazard Codes	Xi