62-97-5
62-97-5 structure
- Name: Diphenmanil (methylsulfate)
- Chemical Name: diphemanil methylsulfate
- CAS Number: 62-97-5
- Molecular Formula: C21H27NO4S
- Molecular Weight: 389.50800
- Catalog: Biochemical Inhibitor Neuronal Signaling AChR antagonist
- Create Date: 2018-09-02 15:41:26
- Modify Date: 2026-07-04 20:13:11
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Diphemanil methylsulfate is a quaternary ammonium anticholinergic. It binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids as well as saliva and sweat.IC50 value: Target: mAChRDiphemanil Methylsulfate exerts its action by primarily binding the muscarinic M3 receptor. M3 receptors are located in the smooth muscles of the blood vessels, as well as in the lungs. This means they cause vasodilation and bronchoconstriction. They are also in the smooth muscles of the gastrointestinal tract (GIT), which help in increasing intestinal motility and dilating sphincters. The M3 receptors are also located in many glands which help to stimulate secretion in salivary glands and other glands of the body.
| Name | diphemanil methylsulfate |
|---|---|
| Synonyms |
Nivelon
Demotil 4-benzhydrylidene-1,1-dimethylpiperidin-1-ium diphenmanilmethylsulfate p-(alpha-phenylbenzylidene)-1,1-dimethylpiperidiniummethylsulfate Variton Diphemanil mesylate 4-Benzhydryliden-1,1-dimethyl-piperidinium,Methylsulfat prantalmethylsulfate n,n-dimethyl-4-piperidylidene-1,1-diphenylmethanemethylsulfate Piperidinium, 4-(diphenylmethylene)-1,1-dimethyl-, methyl sulfate (1:1) 4-(Diphenylmethylene)-1,1-dimethylpiperidin-1-ium Methyl Sulfate Diphenmanil methylsulfate, 10 mM in DMSO diphemanilmethylsulfate vagophemanil Talpran Piperidinium, 4-(diphenylmethylene)-1,1-dimethyl-, methyl sulfate Diphenmethanil prantal vagophemanilmethylsulfate diphenatil diphemanil Diphenmanil methosulfate Diphemanil Methylsulfate //BP Nivelona demotil 4-benzhydrylidene-1,1-dimethylpiperidin-1-ium,methyl sulfate 4-(diphenylmethylene)-1,1-dimethylpiperidiniummethylsulfate iphemanilmethylsulfate nivelona 4-(diphenylmethylene)-1,1-dimethyl-piperidiniumethylsulfate Diphemanil metilsulfate viton DIPHEMANIL METHYLSULFAT diphenmethanil DIPHEMANIL METHYLSULFATE Diphemanil Prantal 4-benzhydrylidene-1,1-dimethyl-piperidin-1-ium DIPHEMANIL METHYLSULFATE DISCON-TINUED 4-benzhydrylidene-1,1-dimethyl-piperidinium,methyl sulfate diphenmethanilmethylsulfate diphemanil metilsulfate Diphemanil Methylsulfate |
| Description | Diphemanil methylsulfate is a quaternary ammonium anticholinergic. It binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids as well as saliva and sweat.IC50 value: Target: mAChRDiphemanil Methylsulfate exerts its action by primarily binding the muscarinic M3 receptor. M3 receptors are located in the smooth muscles of the blood vessels, as well as in the lungs. This means they cause vasodilation and bronchoconstriction. They are also in the smooth muscles of the gastrointestinal tract (GIT), which help in increasing intestinal motility and dilating sphincters. The M3 receptors are also located in many glands which help to stimulate secretion in salivary glands and other glands of the body. |
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| Related Catalog | |
| References |
| Melting Point | 194-195ºC |
|---|---|
| Molecular Formula | C21H27NO4S |
| Molecular Weight | 389.50800 |
| Exact Mass | 389.16600 |
| PSA | 74.81000 |
| LogP | 4.49130 |
CHEMICAL IDENTIFICATION
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