Diphenmanil (methylsulfate)
Modify Date: 2025-08-20 12:11:49
Diphenmanil (methylsulfate) structure
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Common Name | Diphenmanil (methylsulfate) | ||
|---|---|---|---|---|
| CAS Number | 62-97-5 | Molecular Weight | 389.50800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H27NO4S | Melting Point | 194-195ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of Diphenmanil (methylsulfate)Diphemanil methylsulfate is a quaternary ammonium anticholinergic. It binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids as well as saliva and sweat.IC50 value: Target: mAChRDiphemanil Methylsulfate exerts its action by primarily binding the muscarinic M3 receptor. M3 receptors are located in the smooth muscles of the blood vessels, as well as in the lungs. This means they cause vasodilation and bronchoconstriction. They are also in the smooth muscles of the gastrointestinal tract (GIT), which help in increasing intestinal motility and dilating sphincters. The M3 receptors are also located in many glands which help to stimulate secretion in salivary glands and other glands of the body. |
| Name | diphemanil methylsulfate |
|---|---|
| Synonym | More Synonyms |
| Description | Diphemanil methylsulfate is a quaternary ammonium anticholinergic. It binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids as well as saliva and sweat.IC50 value: Target: mAChRDiphemanil Methylsulfate exerts its action by primarily binding the muscarinic M3 receptor. M3 receptors are located in the smooth muscles of the blood vessels, as well as in the lungs. This means they cause vasodilation and bronchoconstriction. They are also in the smooth muscles of the gastrointestinal tract (GIT), which help in increasing intestinal motility and dilating sphincters. The M3 receptors are also located in many glands which help to stimulate secretion in salivary glands and other glands of the body. |
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| Related Catalog | |
| References |
| Melting Point | 194-195ºC |
|---|---|
| Molecular Formula | C21H27NO4S |
| Molecular Weight | 389.50800 |
| Exact Mass | 389.16600 |
| PSA | 74.81000 |
| LogP | 4.49130 |
| InChIKey | BREMLQBSKCSNNH-UHFFFAOYSA-M |
| SMILES | COS(=O)(=O)[O-].C[N+]1(C)CCC(=C(c2ccccc2)c2ccccc2)CC1 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
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|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600
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Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958
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Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482
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| Talpran |
| Diphenmethanil |
| Nivelona |
| Demotil |
| DIPHEMANIL METHYLSULFATE |
| Diphemanil Methylsulfate |
| Variton |
| Diphemanil metilsulfate |
| Diphenmanil (methylsulfate) |
| Diphemanil |
| 4-benzhydrylidene-1,1-dimethyl-piperidinium,methyl sulfate |
| 4-Benzhydryliden-1,1-dimethyl-piperidinium,Methylsulfat |
| 4-benzhydrylidene-1,1-dimethylpiperidin-1-ium,methyl sulfate |
| Prantal |
| Nivelon |