320367-13-3

320367-13-3 structure

Name: Lixisenatide
Chemical Name: lixisenatide
CAS Number: 320367-13-3
Molecular Formula: C₂₁₅H₃₄₇N₆₁O₆₅S
Molecular Weight: 4858.49000
Catalog: Biochemical Peptide
Create Date: 2018-03-20 08:00:00
Modify Date: 2024-01-02 16:03:28
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). Sequence: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-Lys-Lys-Lys-Lys-Lys-Lys-NH2.

Name	lixisenatide
Synonyms	ZP 10 AVE 0010 ZP10A peptide lixisenatide des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)- peptidylpenta-L-lysyl-L-lysinamide AVE0010 Lyxumia UNII-74O62BB01U

Description	Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). Sequence: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-Lys-Lys-Lys-Lys-Lys-Lys-NH2.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Glucagon Receptor Research Areas >> Metabolic Disease Peptides
Target	GLP-1 receptor[1][2].
References	[1]. Ahrén B et al. Postprandial Glucagon Reductions Correlate to Reductions in Postprandial Glucose and Glycated Hemoglobin with Lixisenatide Treatment in Type 2 Diabetes Mellitus: A Post Hoc Analysis. Diabetes Ther. 2016 Jun 18 [2]. Lorenz M, et al. Effects of lixisenatide once daily on gastric emptying in type 2 diabetes--relationship to postprandial glycemia. Regul Pept. 2013 Aug 10;185:1-8.